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NCT03670212 · ClinicalTrials.gov registry record · Phase 1
Investigation of Nicotine Seeking Behavior in Current Smokers
A Phase 1 study, sponsored by Wayne State University.
- Completed
- Registry status
- Phase 1
- Development phase
- 21
- Enrollment target
NCT03670212: Completed Phase 1 study, sponsored by Wayne State University.
NCT03670212 is a Phase 1 study that has completed, run by Wayne State University. The registered enrollment target is 21 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03670212, a Phase 1 study, has completed, sponsored by Wayne State University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 21 participants
- Enrollment target
Study Summary
In this study, 21 non-treatment-seeking cigarette smokers were recruited to investigate the effects of acute stress on brain function and nicotine seeking/self-administration behavior.
Primary Outcome
Participants could earn (via computer mouse 'clicks') money or cigarette puffs (preferred brand; provided by the study) across 11 independent choice trials. At the start of each trial, subjects selected either money or cigarette puffs on a computer screen. After each selection, subjects could earn one unit of that selection by satisfying the computer 'mouse' click requirement. The click requirement increased with each successive unit earned separately for cigarette puffs and money following a pr
Interventions
- DRUG Hydrocortisone
- DRUG Yohimbine Hydrochloride
- DRUG Lactose Monohydrate Powder
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2016-01-07 |
| Est. Completion | 2016-10-04 |
| Phase | Phase 1 |
What the finished NCT03670212 record still lists
NCT03670212 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (65% lower).
The record links to 0 conditions, and to 3 interventions - of which Hydrocortisone is the first listed.
NCT03670212 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03670212 about?
NCT03670212 is a clinical study titled "Investigation of Nicotine Seeking Behavior in Current Smokers". In this study, 21 non-treatment-seeking cigarette smokers were recruited to investigate the effects of acute stress on brain function and nicotine seeking/self-administration behavior.
What is the current status of trial NCT03670212?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 21 participants. The study started on 2016-01-07. Estimated completion is 2016-10-04.
What interventions are being tested in trial NCT03670212?
The interventions under investigation include: Hydrocortisone (DRUG), Yohimbine Hydrochloride (DRUG), Lactose Monohydrate Powder (DRUG).
Who is sponsoring clinical trial NCT03670212?
This trial is sponsored by Wayne State University, which has 163 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03670212's enrollment target sits among peer trials
21 1615th of 2000 higher than 372 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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