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NCT03605901 · ClinicalTrials.gov registry record · Phase 2
Dosing of Methadone for Spine Surgery
A Phase 2 study, sponsored by University of Florida.
- Terminated
- Registry status
- Phase 2
- Development phase
- 21
- Enrollment target
NCT03605901: Clinical Trial Phase 2 study, sponsored by University of Florida.
NCT03605901 is a Phase 2 study that was terminated before completion, run by University of Florida. The registered enrollment target is 21 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (84% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03605901, a Phase 2 study, was terminated before completion, sponsored by University of Florida.
- TERMINATED
- Registry status
- Phase 2
- Development phase
- 21 participants
- Enrollment target
Study Summary
This study compares two methods of dosing methadone for complex spine cases
Primary Outcome
The milligram morphine equivalence (MME) dose was computed for each patient in each 24 hour period using IV (intravenous) administration and by mouth (PO). The outcome measure is defined as the difference between 24 hour periods in the cumulative morphine milligram equivalence dose across both IV (intravenous) administration and by mouth (PO). The difference was calculated by subtracting the MME dose value at the later time point minus the MME value at the earlier time point (e.g., value at 24 h
Interventions
- DRUG Standard dosing of methadone
- DRUG Aliquots of methadone titrated to apnea
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 21 participants |
| Start Date | 2019-03-19 |
| Est. Completion | 2025-05-09 |
| Phase | Phase 2 |
Why NCT03605901 stopped before completion
NCT03605901 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 21 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (84% lower).
The record links to 0 conditions, and to 2 interventions - of which Standard dosing of methadone is the first listed.
NCT03605901 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT03605901 about?
NCT03605901 is a clinical study titled "Dosing of Methadone for Spine Surgery". This study compares two methods of dosing methadone for complex spine cases
What is the current status of trial NCT03605901?
This trial is currently terminated. It is a Phase 2 study. The enrollment target is 21 participants. The study started on 2019-03-19. Estimated completion is 2025-05-09.
What interventions are being tested in trial NCT03605901?
The interventions under investigation include: Standard dosing of methadone (DRUG), Aliquots of methadone titrated to apnea (DRUG).
Who is sponsoring clinical trial NCT03605901?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT03605901's enrollment target sits among peer trials
21 1794th of 2000 higher than 196 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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