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NCT03561220 · ClinicalTrials.gov registry record · NA
A Prospective Comparative Study of Outcomes With Proton and Photon Radiation in Prostate Cancer
A NA study of Prostate Cancer, sponsored by University of Florida.
- Active
- Registry status
- NA
- Development phase
- 3,000
- Enrollment target
- 20
- Study locations
NCT03561220: Active NA study of Prostate Cancer, sponsored by University of Florida.
NCT03561220 is a NA study of Prostate Cancer that is active but no longer recruiting, run by University of Florida. The registered enrollment target is 3,000 participants, above the 604-participant average among 735 other Prostate Cancer trials with a reported enrollment target (397% higher). The trial reports 20 study locations across 9 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03561220, a NA study of Prostate Cancer, is active but no longer recruiting, sponsored by University of Florida.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 3,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study is a large, prospective, pragmatic, controlled comparison of patient-centric outcomes \[quality of life (QOL), toxicity, and disease control\] between parallel cohorts of men with prostate cancer treated simultaneously at proton therapy facilities and at geographically similar conventional (photon-based) radiation facilities using intensity-modulated radiation therapy (IMRT) techniques.
Primary Outcome
EPIC assesses the disease-specific aspects of prostate cancer and its therapies and comprises four summary domains (Urinary, Bowel, Sexual and Hormonal). Factor analysis supports dividing the Urinary Domain Summary Score into two distinct Incontinence and Irritative/Obstructive subscales. In addition, each Domain Summary Score has measurable Function Subscale and Bother Subscale components. Response options for each EPIC item form a Likert scale, and multi-item scale scores are components. Respo
Conditions Studied
Interventions
- RADIATION Standard of Care IMRT (Photon)
- RADIATION Standard of Care Proton Therapy
- RADIATION Proton Arm 1: Standard Proton Therapy
- RADIATION Proton Arm 2: Hypofractionated Proton Therapy
Study Locations (20)
Florida
- Department of Radiation Oncology Davis Cancer Pavilion - Gainesville
- University of Florida Proton Therapy Institute - Jacksonville
- Ackerman Cancer Center - Jacksonville
- Mayo Clinic - Jacksonville
- University of Miami School of Medicine - Miami
- Miami Cancer Institute - Miami
- Orlando Health UF Health Center - Orlando
California
- University of California San Diego - La Jolla
- Proton Therapy Treatment Center - Loma Linda University - Loma Linda
- Sutter Health - Roseville
- California Protons Cancer Therapy Center - San Diego
Illinois
- University of Chicago - Chicago
- Northwestern Medicine Proton Center - Warrenville
Maryland
- Johns Hopkins University - Baltimore
- University of Maryland - College Park
Alabama
- University of Alabama at Birmingham (UAB) - Birmingham
Georgia
- Winship Cancer Institute - Emory University - Atlanta
Kansas
- University of Kansas Medical Center - Lawrence
Kentucky
- University of Louisville - Louisville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,000 participants |
| Start Date | 2018-07-05 |
| Est. Completion | 2027-07-01 |
| Phase | NA |
What the registry record for NCT03561220 still lists
NCT03561220 is an interventional study that assigns participants to a tested intervention. Its 3,000 participants enrollment target places it among the larger protocols in the corpus, above the 604-participant average among 735 other Prostate Cancer trials with a reported enrollment target (397% higher).
The record links to 1 condition, with Prostate Cancer appearing as the primary indexed condition, and to 4 interventions - of which Standard of Care IMRT (Photon) is the first listed.
NCT03561220 names 20 study sites across 9 states, led by Florida, California, Illinois.
Frequently Asked Questions
What is clinical trial NCT03561220 about?
NCT03561220 is a clinical study titled "A Prospective Comparative Study of Outcomes With Proton and Photon Radiation in Prostate Cancer". This study is a large, prospective, pragmatic, controlled comparison of patient-centric outcomes \[quality of life (QOL), toxicity, and disease control\] between parallel cohorts of men with prostate cancer treated simultaneously at proton therapy facilities and at geographically similar conventiona...
What is the current status of trial NCT03561220?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 3,000 participants. The study started on 2018-07-05. Estimated completion is 2027-07-01.
What conditions does trial NCT03561220 study?
This clinical trial studies the following conditions: Prostate Cancer.
What interventions are being tested in trial NCT03561220?
The interventions under investigation include: Standard of Care IMRT (Photon) (RADIATION), Standard of Care Proton Therapy (RADIATION), Proton Arm 1: Standard Proton Therapy (RADIATION), Proton Arm 2: Hypofractionated Proton Therapy (RADIATION).
Who is sponsoring clinical trial NCT03561220?
This trial is sponsored by University of Florida, which has 1,106 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03561220 being conducted?
This trial has 20 study locations across Alabama, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Prostate Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03561220's enrollment target sits among peer trials
3,000 17th of 735 higher than 717 of 735 other Prostate Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Prostate Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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