Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03553095 · ClinicalTrials.gov registry record · NA
Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis
A NA study of Depression and Chronic Periodontitis, sponsored by University of Alabama at Birmingham.
- Active
- Registry status
- NA
- Development phase
- 92
- Enrollment target
- 1
- Study location
NCT03553095: Active NA study of Depression and Chronic Periodontitis, sponsored by University of Alabama at Birmingham.
NCT03553095 is a NA study of Depression and Chronic Periodontitis that is active but no longer recruiting, run by University of Alabama at Birmingham. The registered enrollment target is 92 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03553095, a NA study of Depression and Chronic Periodontitis, is active but no longer recruiting, sponsored by University of Alabama at Birmingham.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 92 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will evaluate whether use of antidepressants can reduce gingival inflammation in patients with periodontal (gum) disease.
Primary Outcome
Measuring oral inflammatory markers in Gingival crevicular fluid (GCF) in patient with chronic periodontitis.
Conditions Studied
Interventions
- PROCEDURE Periodontal Surgery
Study Locations (1)
Alabama
- Unversity of Alabama at Birmingham, School of Dentistry - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 92 participants |
| Start Date | 2018-07-12 |
| Est. Completion | 2026-12-30 |
| Phase | NA |
What the registry record for NCT03553095 still lists
NCT03553095 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 92 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (88% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 1 intervention - of which Periodontal Surgery is the first listed.
NCT03553095 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT03553095 about?
NCT03553095 is a clinical study titled "Comparing Inflammatory Markers in Patients With and Without Depression With Chronic Periodontitis". This study will evaluate whether use of antidepressants can reduce gingival inflammation in patients with periodontal (gum) disease.
What is the current status of trial NCT03553095?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 92 participants. The study started on 2018-07-12. Estimated completion is 2026-12-30.
What conditions does trial NCT03553095 study?
This clinical trial studies the following conditions: Depression, Chronic Periodontitis.
What interventions are being tested in trial NCT03553095?
The interventions under investigation include: Periodontal Surgery (PROCEDURE).
Who is sponsoring clinical trial NCT03553095?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03553095 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03553095's enrollment target sits among peer trials
92 354th of 679 higher than 326 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Reaching Out to Distressed Medical Residents, Fellows and Faculty
RECRUITING · NA
-
IMPACT (IMproving Proactive Approaches for Cancer Survivors' Mental Health Treatment)
RECRUITING · NA
-
Cold and Heat Investigation to Lower Levels of Depression
RECRUITING · NA
-
Dosing rTMS for Depression Post-SCI
RECRUITING · NA
-
Exploring Virtual Reality Adventure Training Exergaming
RECRUITING · NA
-
Brief Interventions for Coping with Distress
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03184545 · 92 participants · Phase 3
Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome
- NCT04172532 · 92 participants · Phase 1
Testing the Addition of a New Anti-cancer Drug, M3814 (Peposertib), to the Usual Radiotherapy in Patients With Locally Advanced Pancreatic Cancer
- NCT04508088 · 92 participants
Skeletal Health and Bone Marrow Composition in Newly Diagnosed Adolescents With Crohn Disease
- NCT04840602 · 92 participants · Phase 2
Testing the Combination of Venetoclax and Rituximab, in Comparison to the Usual Treatment (Ibrutinib Plus Rituximab or Zanubrutinib Alone) for Waldenstrom's Macroglobulinemia/Lymphoplasmacytic Lymphoma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT06358040 · started 2026-10 · NA
Opioid Dispenser for Microdiscectomy/Laminectomy