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NCT03547700 · ClinicalTrials.gov registry record · Phase 1

Study of Ixazomib and Romidepsin in Peripheral T-cell Lymphoma (PTCL)

A Phase 1 study of Lymphoma, T-Cell, Peripheral, sponsored by Ryan Wilcox.

Active
Registry status
Phase 1
Development phase
11
Enrollment target
7
Study locations

NCT03547700 is a Phase 1 study of Lymphoma, T-Cell, Peripheral that is active but no longer recruiting, run by Ryan Wilcox. The registered enrollment target is 11 participants, below the 331-participant average among 6 other Lymphoma, T-Cell, Peripheral trials with a reported enrollment target (97% lower). The trial reports 7 study locations across 6 states.

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The verdict

NCT03547700, a Phase 1 study of Lymphoma, T-Cell, Peripheral, is active but no longer recruiting, sponsored by Ryan Wilcox.

ACTIVE NOT RECRUITING
Registry status
Phase 1
Development phase
11 participants
Enrollment target
7
Study locations

Study Summary

Single arm phase I/II study of ixazomib and romidepsin in relapsed/refractory PTCL. Each cycle is 28 days. Patients will continue to receive therapy until progressive disease, unacceptable toxicity, or if any other withdrawal criteria are met. The phase I study includes three dose levels. The phase II study will include treatment with ixazomib and romidepsin at the MTD established in the Phase I study.

Interventions

  • DRUG Romidepsin
  • DRUG Ixazomib

Study Locations (7)

Michigan

  • University of Michigan Comprehensive Cancer Center - Ann Arbor
  • Karmanos Cancer Center (Wayne State University) - Detroit

Illinois

  • University of Illinois Cancer Center - Chicago

Indiana

  • Indiana University Melvin and Bren Simon Cancer Center - Indianapolis

Iowa

  • University of Iowa Hospitals and Clinics - Iowa City

Minnesota

  • University of Minnesota - Minneapolis

New Jersey

  • Rutgers Cancer Institute of New Jersey - New Brunswick

Trial Details

FieldValue
Enrollment Target 11 participants
Start Date 2018-09-26
Est. Completion 2021-07
Phase Phase 1

Sponsor

Ryan Wilcox

1 total trials

What the Registry Record Tells You About NCT03547700

The ClinicalTrials.gov registry entry for NCT03547700 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 11 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 331-participant average among 6 other Lymphoma, T-Cell, Peripheral trials with a reported enrollment target (97% lower). The listed sponsor is Ryan Wilcox, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Lymphoma, T-Cell, Peripheral appearing as the primary indexed condition, and to 2 interventions - of which Romidepsin is the first listed.

NCT03547700 reports 7 study locations spanning 6 distinct geographic areas - top geographies include Michigan, Illinois, Indiana.

Frequently Asked Questions

What is clinical trial NCT03547700 about?

NCT03547700 is a clinical study titled "Study of Ixazomib and Romidepsin in Peripheral T-cell Lymphoma (PTCL)". Single arm phase I/II study of ixazomib and romidepsin in relapsed/refractory PTCL. Each cycle is 28 days. Patients will continue to receive therapy until progressive disease, unacceptable toxicity, or if any other withdrawal criteria are met. The phase I study includes three dose levels. The phase ...

What is the current status of trial NCT03547700?

This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 11 participants. The study started on 2018-09-26. Estimated completion is 2021-07.

What conditions does trial NCT03547700 study?

This clinical trial studies the following conditions: Lymphoma, T-Cell, Peripheral.

What interventions are being tested in trial NCT03547700?

The interventions under investigation include: Romidepsin (DRUG), Ixazomib (DRUG).

Who is sponsoring clinical trial NCT03547700?

This trial is sponsored by Ryan Wilcox, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03547700 being conducted?

This trial has 7 study locations across Illinois, Indiana, Iowa, Michigan, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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