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NCT06561048 · ClinicalTrials.gov registry record · Phase 3
Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma
A Phase 3 study of Angioimmunoblastic T-cell Lymphoma and Lymphoma, T-Cell, sponsored by Corvus Pharmaceuticals.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 150
- Enrollment target
- 17
- Study locations
NCT06561048: Recruiting Phase 3 study of Angioimmunoblastic T-cell Lymphoma and Lymphoma, T-Cell, sponsored by Corvus Pharmaceuticals.
NCT06561048 is a Phase 3 study of Angioimmunoblastic T-cell Lymphoma and Lymphoma, T-Cell that is actively recruiting participants, run by Corvus Pharmaceuticals. The registered enrollment target is 150 participants, above the 63-participant average among 21 other Angioimmunoblastic T-cell Lymphoma trials with a reported enrollment target (138% higher). The trial reports 17 study locations across 15 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06561048, a Phase 3 study of Angioimmunoblastic T-cell Lymphoma and Lymphoma, T-Cell, is actively recruiting participants, sponsored by Corvus Pharmaceuticals.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 150 participants
- Enrollment target
- 17
- Study locations
Study Summary
A Phase 3, randomized, 2-arm, open-label, multicenter, stratified study of soquelitinib versus physician's choice standard of care (SOC) treatment (selected single agents) in participants with relapsed/refractory (R/R) peripheral T-cell lymphoma not otherwise specified (PTCL-NOS), follicular helper T-cell lymphomas (FHTCLs), or systemic anaplastic large-cell lymphoma (sALCL).
Primary Outcome
Time from first study treatment to first occurrence of progression (as assessed by the Independent Review Committee) or death, whichever occurs first
Conditions Studied
Interventions
- DRUG Belinostat
- DRUG Pralatrexate
- DRUG Soquelitinib
Study Locations (17)
California
- City of Hope National Medical Center - Duarte
- University of California, Irvine - Irvine
- University of California San Francisco - San Francisco
Connecticut
- Yale University - New Haven
Georgia
- Emory University - Atlanta
Iowa
- University of Iowa - Iowa City
Maryland
- University of Maryland Medical Center - Baltimore
Massachusetts
- Massachusetts General Hospital - Boston
Michigan
- University of Michigan - Ann Arbor
Missouri
- Washington University in St. Louis - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 150 participants |
| Start Date | 2024-10-02 |
| Est. Completion | 2028-07 |
| Phase | Phase 3 |
What NCT06561048 shows while recruiting
NCT06561048 is an interventional study that assigns participants to a tested intervention. The registered 150 participants enrollment target is mid-sized for trials with a published cap, above the 63-participant average among 21 other Angioimmunoblastic T-cell Lymphoma trials with a reported enrollment target (138% higher).
The record links to 7 conditions, with Angioimmunoblastic T-cell Lymphoma appearing as the primary indexed condition, and to 3 interventions - of which Belinostat is the first listed.
NCT06561048 lists 17 locations in 15 states (California, Connecticut, Georgia).
Frequently Asked Questions
What is clinical trial NCT06561048 about?
NCT06561048 is a clinical study titled "Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell Lymphoma". A Phase 3, randomized, 2-arm, open-label, multicenter, stratified study of soquelitinib versus physician's choice standard of care (SOC) treatment (selected single agents) in participants with relapsed/refractory (R/R) peripheral T-cell lymphoma not otherwise specified (PTCL-NOS), follicular helper ...
What is the current status of trial NCT06561048?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2024-10-02. Estimated completion is 2028-07.
What conditions does trial NCT06561048 study?
This clinical trial studies the following conditions: Angioimmunoblastic T-cell Lymphoma, Lymphoma, T-Cell, Lymphoma, T-Cell, Peripheral, Peripheral T-Cell Lymphoma, Not Otherwise Specified, Follicular T-Cell Lymphoma.
What interventions are being tested in trial NCT06561048?
The interventions under investigation include: Belinostat (DRUG), Pralatrexate (DRUG), Soquelitinib (DRUG).
Who is sponsoring clinical trial NCT06561048?
This trial is sponsored by Corvus Pharmaceuticals, which has 10 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06561048 being conducted?
This trial has 17 study locations across California, Connecticut, Georgia, Iowa, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06561048's enrollment target sits among peer trials
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participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Angioimmunoblastic T-cell Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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