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NCT03495323 · ClinicalTrials.gov registry record · Phase 1

A Study of Prexasertib (LY2606368), CHK1 Inhibitor, and LY3300054, PD-L1 Inhibitor, in Patients With Advanced Solid Tumors

A Phase 1 study of Cancer, sponsored by Dana-Farber Cancer Institute.

Completed
Registry status
Phase 1
Development phase
17
Enrollment target
1
Study location

NCT03495323: Completed Phase 1 study of Cancer, sponsored by Dana-Farber Cancer Institute.

NCT03495323 is a Phase 1 study of Cancer that has completed, run by Dana-Farber Cancer Institute. The registered enrollment target is 17 participants, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03495323, a Phase 1 study of Cancer, has completed, sponsored by Dana-Farber Cancer Institute.

COMPLETED
Registry status
Phase 1
Development phase
17 participants
Enrollment target
1
Study location

Study Summary

This research study is studying a combination of a targeted therapy and an immune therapy as a possible treatment. The drugs involved in this study are: * Prexasertib (LY2606368) * LY3300054

Conditions Studied

Interventions

  • DRUG LY3300054
  • DRUG Prexasertib

Study Locations (1)

Massachusetts

  • Dana Farber Cancer Institute - Boston

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2018-05-16
Est. Completion 2021-02-01
Phase Phase 1
Dana-Farber Cancer Institute

781 total trials

What the finished NCT03495323 record still lists

NCT03495323 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 3,491-participant average among 615 other Cancer trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Cancer appearing as the primary indexed condition, and to 2 interventions - of which LY3300054 is the first listed.

NCT03495323 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT03495323 about?

NCT03495323 is a clinical study titled "A Study of Prexasertib (LY2606368), CHK1 Inhibitor, and LY3300054, PD-L1 Inhibitor, in Patients With Advanced Solid Tumors". This research study is studying a combination of a targeted therapy and an immune therapy as a possible treatment. The drugs involved in this study are: * Prexasertib (LY2606368) * LY3300054

What is the current status of trial NCT03495323?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2018-05-16. Estimated completion is 2021-02-01.

What conditions does trial NCT03495323 study?

This clinical trial studies the following conditions: Cancer.

What interventions are being tested in trial NCT03495323?

The interventions under investigation include: LY3300054 (DRUG), Prexasertib (DRUG).

Who is sponsoring clinical trial NCT03495323?

This trial is sponsored by Dana-Farber Cancer Institute, which has 781 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03495323 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03495323's enrollment target sits among peer trials

17 574th of 615 higher than 36 of 615 other Cancer trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03495323, the US trial registry maintained by the National Library of Medicine. NCT03495323 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.