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NCT03410056 · ClinicalTrials.gov registry record · Phase 1

Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis

A Phase 1 study, sponsored by Amgen.

Terminated
Registry status
Phase 1
Development phase
36
Enrollment target

NCT03410056 is a Phase 1 study that was terminated before completion, run by Amgen. The registered enrollment target is 36 participants.

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The verdict

NCT03410056, a Phase 1 study, was terminated before completion, sponsored by Amgen.

TERMINATED
Registry status
Phase 1
Development phase
36 participants
Enrollment target

Study Summary

Phase 1b. To evaluate the safety and tolerability of subcutaneous (SC) dose administrations of Efavaleukin alfa in subjects with active rheumatoid arthritis (RA). Phase 2a. To evaluate the efficacy of Efavaleukin alfa at week 12 as measured by the American College of Rheumatology 20 percent improvement criteria (ACR 20) in adult subjects with moderate to severe RA.

Interventions

  • DRUG Placebo
  • DRUG Efavaleukin alfa

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2018-05-22
Est. Completion 2020-05-13
Phase Phase 1

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT03410056

The ClinicalTrials.gov registry entry for NCT03410056 describes a study currently listed as terminated, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT03410056 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT03410056 about?

NCT03410056 is a clinical study titled "Safety and Efficacy of Efavaleukin Alfa in Subjects With Active Rheumatoid Arthritis". Phase 1b. To evaluate the safety and tolerability of subcutaneous (SC) dose administrations of Efavaleukin alfa in subjects with active rheumatoid arthritis (RA). Phase 2a. To evaluate the efficacy of Efavaleukin alfa at week 12 as measured by the American College of Rheumatology 20 percent improve...

What is the current status of trial NCT03410056?

This trial is currently terminated. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2018-05-22. Estimated completion is 2020-05-13.

What interventions are being tested in trial NCT03410056?

The interventions under investigation include: Placebo (DRUG), Efavaleukin alfa (DRUG).

Who is sponsoring clinical trial NCT03410056?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.