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NCT03404258 · ClinicalTrials.gov registry record
ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis
A clinical trial of Single-ventricle and Metabolomics, sponsored by University of Colorado, Denver.
- Recruiting
- Registry status
- 50
- Enrollment target
- 1
- Study location
NCT03404258: Recruiting study of Single-ventricle and Metabolomics, sponsored by University of Colorado, Denver.
NCT03404258 is a study of Single-ventricle and Metabolomics that is actively recruiting participants, run by University of Colorado, Denver. The registered enrollment target is 50 participants, below the 84-participant average among 17 other Single-ventricle trials with a reported enrollment target (40% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03404258, a study of Single-ventricle and Metabolomics, is actively recruiting participants, sponsored by University of Colorado, Denver.
- RECRUITING
- Registry status
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a novel preliminary study of biomarkers of pathologic pre-operative pulmonary vascular development, elevated pre-operative Pulmonary Vascular Resistance Index (PVRi), and complications associated with decreased post-operative pulmonary blood flow in single ventricle patients undergoing superior cavo-pulmonary anastomosis (SCPA). The study will utilize a combined targeted and untargeted approach to both optimize translation of a promising existing biomarker and efficiently identify novel biomarkers and potential therapeutic targets in this population.
Conditions Studied
Interventions
- OTHER Research Blood Sampling
Study Locations (1)
Colorado
- Children's Hospital Colorado - Denver
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2018-02-10 |
| Est. Completion | 2025-12-31 |
What NCT03404258 shows while recruiting
NCT03404258 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 84-participant average among 17 other Single-ventricle trials with a reported enrollment target (40% lower).
The record links to 5 conditions, with Single-ventricle appearing as the primary indexed condition, and to 1 intervention - of which Research Blood Sampling is the first listed.
NCT03404258 reports a single indexed study location in Colorado.
Frequently Asked Questions
What is clinical trial NCT03404258 about?
NCT03404258 is a clinical study titled "ET1 Concentration, Metabolic Pathway Activation, and Pulmonary Blood Flow in Infants Undergoing Superior Cavo-Pulmonary Anastomosis". This is a novel preliminary study of biomarkers of pathologic pre-operative pulmonary vascular development, elevated pre-operative Pulmonary Vascular Resistance Index (PVRi), and complications associated with decreased post-operative pulmonary blood flow in single ventricle patients undergoing super...
What is the current status of trial NCT03404258?
This trial is currently recruiting. The enrollment target is 50 participants. The study started on 2018-02-10. Estimated completion is 2025-12-31.
What conditions does trial NCT03404258 study?
This clinical trial studies the following conditions: Single-ventricle, Metabolomics, Pulmonary Vascular Resistance Abnormality, Superior Cavo-Pulmonary Anastomosis, Endothelin.
What interventions are being tested in trial NCT03404258?
The interventions under investigation include: Research Blood Sampling (OTHER).
Who is sponsoring clinical trial NCT03404258?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03404258 being conducted?
This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Where NCT03404258's enrollment target sits among peer trials
50 8th of 17 higher than 9 of 17 other Single-ventricle trials
participants (enrollment target), bucketed by value
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