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NCT03347279 · ClinicalTrials.gov registry record · Phase 3
Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma
A Phase 3 study of Asthma, sponsored by AstraZeneca.
- Completed
- Registry status
- Phase 3
- Development phase
- 1,061
- Enrollment target
- 20
- Study locations
NCT03347279: Completed Phase 3 study of Asthma, sponsored by AstraZeneca.
NCT03347279 is a Phase 3 study of Asthma that has completed, run by AstraZeneca. The registered enrollment target is 1,061 participants, below the 1,561-participant average among 374 other Asthma trials with a reported enrollment target (32% lower). The trial reports 20 study locations across 6 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03347279, a Phase 3 study of Asthma, has completed, sponsored by AstraZeneca.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 1,061 participants
- Enrollment target
- 20
- Study locations
Study Summary
A Multicentre, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults and Adolescents with Severe Uncontrolled Asthma
Primary Outcome
The annual exacerbation rate is based on unadjudicated exacerbations reported by the investigator in the eCRF. The analysis is based on the primary population (Full Analysis Set)
Conditions Studied
Interventions
- OTHER Placebo
- BIOLOGICAL Experimental: Tezepelumab
Study Locations (20)
California
- Research Site - Bakersfield
- Research Site - Encinitas
- Research Site - Huntington Beach
- Research Site - Long Beach
- Research Site - Los Angeles
- Research Site - Mission Viejo
- Research Site - Newport Beach
- Research Site - Northridge
- Research Site - Palm Desert
- Research Site - Rolling Hills Estates
- Research Site - Walnut Creek
- Research Site - Westminster
Alabama
- Research Site - Dothan
- Research Site - Foley
Arizona
- Research Site - Gilbert
- Research Site - Tucson
Florida
- Research Site - Celebration
- Research Site - Kissimmee
Colorado
- Research Site - Denver
Connecticut
- Research Site - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,061 participants |
| Start Date | 2017-11-23 |
| Est. Completion | 2020-11-12 |
| Phase | Phase 3 |
What the finished NCT03347279 record still lists
NCT03347279 is an interventional study that assigns participants to a tested intervention. Its 1,061 participants enrollment target places it among the larger protocols in the corpus, below the 1,561-participant average among 374 other Asthma trials with a reported enrollment target (32% lower).
The record links to 1 condition, with Asthma appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT03347279 names 20 study sites across 6 states, led by California, Alabama, Arizona.
Frequently Asked Questions
What is clinical trial NCT03347279 about?
NCT03347279 is a clinical study titled "Study to Evaluate Tezepelumab in Adults & Adolescents With Severe Uncontrolled Asthma". A Multicentre, Randomized, Double-Blind, Placebo Controlled, Parallel Group, Phase 3 Study to Evaluate the Efficacy and Safety of Tezepelumab in Adults and Adolescents with Severe Uncontrolled Asthma
What is the current status of trial NCT03347279?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,061 participants. The study started on 2017-11-23. Estimated completion is 2020-11-12.
What conditions does trial NCT03347279 study?
This clinical trial studies the following conditions: Asthma.
What interventions are being tested in trial NCT03347279?
The interventions under investigation include: Placebo (OTHER), Experimental: Tezepelumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT03347279?
This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03347279 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Asthma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03347279's enrollment target sits among peer trials
1,061 39th of 374 higher than 336 of 374 other Asthma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Asthma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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