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NCT07140172 · ClinicalTrials.gov registry record · NA
Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery
A NA study of Breast Cancer, sponsored by University Hospital, Basel, Switzerland.
- Recruiting
- Registry status
- NA
- Development phase
- 1,060
- Enrollment target
- 20
- Study locations
NCT07140172: Recruiting NA study of Breast Cancer, sponsored by University Hospital, Basel, Switzerland.
NCT07140172 is a NA study of Breast Cancer that is actively recruiting participants, run by University Hospital, Basel, Switzerland. The registered enrollment target is 1,060 participants, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (62% lower). The trial reports 20 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07140172, a NA study of Breast Cancer, is actively recruiting participants, sponsored by University Hospital, Basel, Switzerland.
- RECRUITING
- Registry status
- NA
- Development phase
- 1,060 participants
- Enrollment target
- 20
- Study locations
Study Summary
This trial is to investigate if in patients with clinically node positive breast cancer undergoing upfront surgery, treatment with TAS and ART is superior to ALND in terms of arm-related Quality of Life (QoL) and occurrence of lymphedema two years after randomization.
Primary Outcome
The arm subscale (ARM) of the FACT-B+4 is used to assess arm-related QoL.The FACT-B comprises five subscales: physical well-being (seven items), social well-being (seven items), emotional well-being (six items), functional well-being (seven items), and concerns specific to patients with breast cancer (13 items). The FACT-B+4 questionnaire consists of the FACT-B subscales and the additional ARM subscale including five questions related to arm morbidity with four additional validated arm morbidity
Conditions Studied
Interventions
- PROCEDURE Axillary lymph node dissection (ALND)
- PROCEDURE Axillary radiotherapy (ART)
Study Locations (20)
Other
- Sanatorio Parque Breast Cancer Center - Rosario
- KH Dornbirn - Dornbirn
- LKH Feldkirch - Feldkirch
- MUI - Univ. Klinik f. Frauenheilkunde Innsbruck - Innsbruck
- CIUSSS du Centre Ouest-de-l 'Ile-de-Montréal - Montreal
- Breast Centre of Clinical Hospital, Rijeka - Rijeka
- HRUHC Sestre milosdrnice, Zagreb - Zagreb
- Brustzentrum Heidelberg Klinik St. Elisabeth GmbH - Heidelberg
- HELIOS Universitätsklinikum Wuppertal - Wuppertal
- "Alexandra" Hospital, Athens - Athens
- University Hospital of Heraklion - Heraklion
- University Hospital of Larissa - Larissa
- Policlinico Universitario "Agostino Gemelli - Rome
- Gangnam Severance Hospital - Seoul
- Samsung Medical Center - Seoul
- Kantonsspital Baden - Baden
- Breast Surgery Service, University Hospital Basel - Basel
- Clinique des Grangettes - Chêne-Bougeries
- Spital Thurgau - Frauenfeld
North Carolina
- Duke University/Duke Cancer Center - Durham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,060 participants |
| Start Date | 2026-01-01 |
| Est. Completion | 2037-12 |
| Phase | NA |
What NCT07140172 shows while recruiting
NCT07140172 is an interventional study that assigns participants to a tested intervention. Its 1,060 participants enrollment target places it among the larger protocols in the corpus, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (62% lower).
The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Axillary lymph node dissection (ALND) is the first listed.
NCT07140172 names 20 study sites across 2 states, led by Other, North Carolina.
Frequently Asked Questions
What is clinical trial NCT07140172 about?
NCT07140172 is a clinical study titled "Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery". This trial is to investigate if in patients with clinically node positive breast cancer undergoing upfront surgery, treatment with TAS and ART is superior to ALND in terms of arm-related Quality of Life (QoL) and occurrence of lymphedema two years after randomization.
What is the current status of trial NCT07140172?
This trial is currently recruiting. It is a NA study. The enrollment target is 1,060 participants. The study started on 2026-01-01. Estimated completion is 2037-12.
What conditions does trial NCT07140172 study?
This clinical trial studies the following conditions: Breast Cancer.
What interventions are being tested in trial NCT07140172?
The interventions under investigation include: Axillary lymph node dissection (ALND) (PROCEDURE), Axillary radiotherapy (ART) (PROCEDURE).
Who is sponsoring clinical trial NCT07140172?
This trial is sponsored by University Hospital, Basel, Switzerland, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07140172 being conducted?
This trial has 20 study locations across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Breast Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07140172's enrollment target sits among peer trials
1,060 114th of 1224 higher than 1,111 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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