Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07140172 · ClinicalTrials.gov registry record · NA

Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery

A NA study of Breast Cancer, sponsored by University Hospital, Basel, Switzerland.

Recruiting
Registry status
NA
Development phase
1,060
Enrollment target
20
Study locations

NCT07140172 is a NA study of Breast Cancer that is actively recruiting participants, run by University Hospital, Basel, Switzerland. The registered enrollment target is 1,060 participants, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (62% lower). The trial reports 20 study locations across 2 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07140172, a NA study of Breast Cancer, is actively recruiting participants, sponsored by University Hospital, Basel, Switzerland.

RECRUITING
Registry status
NA
Development phase
1,060 participants
Enrollment target
20
Study locations

Study Summary

This trial is to investigate if in patients with clinically node positive breast cancer undergoing upfront surgery, treatment with TAS and ART is superior to ALND in terms of arm-related Quality of Life (QoL) and occurrence of lymphedema two years after randomization.

Conditions Studied

Interventions

  • PROCEDURE Axillary lymph node dissection (ALND)
  • PROCEDURE Axillary radiotherapy (ART)

Study Locations (20)

Other

  • Sanatorio Parque Breast Cancer Center - Rosario
  • KH Dornbirn - Dornbirn
  • LKH Feldkirch - Feldkirch
  • MUI - Univ. Klinik f. Frauenheilkunde Innsbruck - Innsbruck
  • CIUSSS du Centre Ouest-de-l 'Ile-de-Montréal - Montreal
  • Breast Centre of Clinical Hospital, Rijeka - Rijeka
  • HRUHC Sestre milosdrnice, Zagreb - Zagreb
  • Brustzentrum Heidelberg Klinik St. Elisabeth GmbH - Heidelberg
  • HELIOS Universitätsklinikum Wuppertal - Wuppertal
  • "Alexandra" Hospital, Athens - Athens
  • University Hospital of Heraklion - Heraklion
  • University Hospital of Larissa - Larissa
  • Policlinico Universitario "Agostino Gemelli - Rome
  • Gangnam Severance Hospital - Seoul
  • Samsung Medical Center - Seoul
  • Kantonsspital Baden - Baden
  • Breast Surgery Service, University Hospital Basel - Basel
  • Clinique des Grangettes - Chêne-Bougeries
  • Spital Thurgau - Frauenfeld

North Carolina

  • Duke University/Duke Cancer Center - Durham

Trial Details

FieldValue
Enrollment Target 1,060 participants
Start Date 2026-01-01
Est. Completion 2037-12
Phase NA

What the Registry Record Tells You About NCT07140172

The ClinicalTrials.gov registry entry for NCT07140172 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 1,060 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,802-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (62% lower). The listed sponsor is University Hospital, Basel, Switzerland, which has 12 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Breast Cancer appearing as the primary indexed condition, and to 2 interventions - of which Axillary lymph node dissection (ALND) is the first listed.

NCT07140172 reports 20 study locations spanning 2 distinct geographic areas - top geographies include Other, North Carolina.

Frequently Asked Questions

What is clinical trial NCT07140172 about?

NCT07140172 is a clinical study titled "Axillary Radiotherapy or Axillary Lymph Node Dissection in Patients With Clinically Node- Positive Breast Cancer Undergoing Upfront Tailored Axillary Surgery". This trial is to investigate if in patients with clinically node positive breast cancer undergoing upfront surgery, treatment with TAS and ART is superior to ALND in terms of arm-related Quality of Life (QoL) and occurrence of lymphedema two years after randomization.

What is the current status of trial NCT07140172?

This trial is currently recruiting. It is a NA study. The enrollment target is 1,060 participants. The study started on 2026-01-01. Estimated completion is 2037-12.

What conditions does trial NCT07140172 study?

This clinical trial studies the following conditions: Breast Cancer.

What interventions are being tested in trial NCT07140172?

The interventions under investigation include: Axillary lymph node dissection (ALND) (PROCEDURE), Axillary radiotherapy (ART) (PROCEDURE).

Who is sponsoring clinical trial NCT07140172?

This trial is sponsored by University Hospital, Basel, Switzerland, which has 12 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07140172 being conducted?

This trial has 20 study locations across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Breast Cancer

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.