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NCT03338062 · ClinicalTrials.gov registry record · NA
A Pilot Study to Assess Theragnostically Planned Liver Radiation to Optimize Radiation Therapy
A NA study of Hepatocellular Carcinoma and Liver Cancer, sponsored by Indiana University.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
- 1
- Study location
NCT03338062: Completed NA study of Hepatocellular Carcinoma and Liver Cancer, sponsored by Indiana University.
NCT03338062 is a NA study of Hepatocellular Carcinoma and Liver Cancer that has completed, run by Indiana University. The registered enrollment target is 15 participants, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03338062, a NA study of Hepatocellular Carcinoma and Liver Cancer, has completed, sponsored by Indiana University.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to compare radiation treatment plans that are designed for patients with liver cancer. One treatment plan will be created using routine procedures and scans normally performed for radiation treatment planning. The other treatment plan will be created using routine procedures with the addition of two imaging scans; a HIDA (Hepatobiliary Iminodiacetic Acid) scan and an MRI (Magnetic Resonance Imaging) scan. This study will evaluate if adding these imaging scans to treatment planning can reduce the amount of radiation to healthy liver tissue during treatment.
Primary Outcome
The functional reserve of the liver for both standard SBRT planning and theragnostic SBRT planning will be calculated for each patient regardless of which plan was ultimately chosen. Function reserve of the liver = (number of counts outside 15 Gy isodose line / total number of counts within the liver) \* global liver function; where global liver function is the rate of liver uptake (%/min) between 150 to 300 seconds normalized to body surface area (m\^2) using the Du Bois method. The difference
Conditions Studied
Interventions
- DIAGNOSTIC_TEST Hepatobiliary Iminodiacetic Acid (HIDA) scan
Study Locations (1)
Indiana
- Indiana University Melvin & Bren Simon Cancer Center - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2017-06-13 |
| Est. Completion | 2019-09-02 |
| Phase | NA |
What the finished NCT03338062 record still lists
NCT03338062 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 257-participant average among 145 other Hepatocellular Carcinoma trials with a reported enrollment target (94% lower).
The record links to 3 conditions, with Hepatocellular Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which Hepatobiliary Iminodiacetic Acid (HIDA) scan is the first listed.
NCT03338062 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT03338062 about?
NCT03338062 is a clinical study titled "A Pilot Study to Assess Theragnostically Planned Liver Radiation to Optimize Radiation Therapy". The purpose of this study is to compare radiation treatment plans that are designed for patients with liver cancer. One treatment plan will be created using routine procedures and scans normally performed for radiation treatment planning. The other treatment plan will be created using routine proced...
What is the current status of trial NCT03338062?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2017-06-13. Estimated completion is 2019-09-02.
What conditions does trial NCT03338062 study?
This clinical trial studies the following conditions: Hepatocellular Carcinoma, Liver Cancer, Cholangiocarcinoma.
What interventions are being tested in trial NCT03338062?
The interventions under investigation include: Hepatobiliary Iminodiacetic Acid (HIDA) scan (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT03338062?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03338062 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hepatocellular Carcinoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03338062's enrollment target sits among peer trials
15 135th of 145 higher than 10 of 145 other Hepatocellular Carcinoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hepatocellular Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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