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NCT03335371 · ClinicalTrials.gov registry record · Phase 1

Evaluation of TTP399 in Patients With Type 1 Diabetes

A Phase 1 study of Diabetes Mellitus, Type 1, sponsored by vTv Therapeutics.

Completed
Registry status
Phase 1
Development phase
115
Enrollment target
15
Study locations

NCT03335371 is a Phase 1 study of Diabetes Mellitus, Type 1 that has completed, run by vTv Therapeutics. The registered enrollment target is 115 participants, below the 1,265-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (91% lower). The trial reports 15 study locations across 9 states.

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The verdict

NCT03335371, a Phase 1 study of Diabetes Mellitus, Type 1, has completed, sponsored by vTv Therapeutics.

COMPLETED
Registry status
Phase 1
Development phase
115 participants
Enrollment target
15
Study locations

Study Summary

The purpose of this study is to evaluate the safety and efficacy of TTP399 in Type 1 diabetics. This study will be in 2 phases: phase 1 will evaluate the safety of different TTP399 dosage regimens over 1 week of daily dosing. Phase 2 will evaluate the safety and efficacy of a TTP399 dosing regimen over 12 weeks of daily dosing.

Conditions Studied

Diabetes Mellitus, Type 1

Interventions

  • DRUG Placebo Oral Tablet
  • DRUG TTP399

Study Locations (15)

North Carolina

  • Mountain Diabetes and Endocrine Center - Asheville
  • UNC Diabetes Care Center - Chapel Hill
  • Duke University Diabetes Research Clinic - Durham
  • Diabetes & Endocrinology Consultants - Morehead City
  • PMG Research of Wilmington - Wilmington
  • Wake Forest - Winston-Salem

California

  • USC Westside Center for Diabetes - Beverly Hills
  • AMCR Institute - Escondido

Colorado

  • University of Colorado Barbara Davis Center - Aurora

Georgia

  • Atlanta Diabetes Associate - Atlanta

Idaho

  • Rocky Mountain Diabetes Center - Idaho Falls

Iowa

  • Iowa Diabetes Research - West Des Moines

Oklahoma

  • Intend Research - Norman

Texas

  • Dallas Diabetes Research Center - Dallas

Trial Details

FieldValue
Enrollment Target 115 participants
Start Date 2017-10-25
Est. Completion 2020-01-06
Phase Phase 1

Sponsor

vTv Therapeutics

13 total trials

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What the Registry Record Tells You About NCT03335371

The ClinicalTrials.gov registry entry for NCT03335371 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 115 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,265-participant average among 118 other Diabetes Mellitus, Type 1 trials with a reported enrollment target (91% lower). The listed sponsor is vTv Therapeutics, which has 13 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Diabetes Mellitus, Type 1 appearing as the primary indexed condition, and to 2 interventions - of which Placebo Oral Tablet is the first listed.

NCT03335371 reports 15 study locations spanning 9 distinct geographic areas - top geographies include North Carolina, California, Colorado.

Frequently Asked Questions

What is clinical trial NCT03335371 about?

NCT03335371 is a clinical study titled "Evaluation of TTP399 in Patients With Type 1 Diabetes". The purpose of this study is to evaluate the safety and efficacy of TTP399 in Type 1 diabetics. This study will be in 2 phases: phase 1 will evaluate the safety of different TTP399 dosage regimens over 1 week of daily dosing. Phase 2 will evaluate the safety and efficacy of a TTP399 dosing regimen o...

What is the current status of trial NCT03335371?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 115 participants. The study started on 2017-10-25. Estimated completion is 2020-01-06.

What conditions does trial NCT03335371 study?

This clinical trial studies the following conditions: Diabetes Mellitus, Type 1.

What interventions are being tested in trial NCT03335371?

The interventions under investigation include: Placebo Oral Tablet (DRUG), TTP399 (DRUG).

Who is sponsoring clinical trial NCT03335371?

This trial is sponsored by vTv Therapeutics, which has 13 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03335371 being conducted?

This trial has 15 study locations across California, Colorado, Georgia, Idaho, Iowa. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.