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NCT03300726 · ClinicalTrials.gov registry record

Synaptic Injury and Functional Connectivity in Alzheimer's Disease

A clinical trial of Alzheimer Disease, Late Onset, sponsored by Ohio State University.

Completed
Registry status
35
Enrollment target
1
Study location

NCT03300726 is a study of Alzheimer Disease, Late Onset that has completed, run by Ohio State University. The registered enrollment target is 35 participants, below the 2,296-participant average among 7 other Alzheimer Disease, Late Onset trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03300726, a study of Alzheimer Disease, Late Onset, has completed, sponsored by Ohio State University.

COMPLETED
Registry status
35 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to examine cross-sectional associations between CSF markers of synaptic injury (Ng and SNAP-25) and functional connectivity in default and semantic memory networks using 3T- fMRI in individuals with MCI (i.e. the earliest clinically detectable stage of cognitive impairment) due to AD or mild AD dementia (CDR 0.5-1; n=20) and cognitively normal controls (CDR 0; n=20).

Conditions Studied

Alzheimer Disease, Late Onset

Interventions

  • DIAGNOSTIC_TEST CSF analysis
  • RADIATION Functional MRI

Study Locations (1)

Ohio

  • The Ohio State University Wexner Medical Center - Columbus

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2018-02-12
Est. Completion 2021-09-22

Sponsor

Ohio State University

552 total trials

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What the Registry Record Tells You About NCT03300726

The ClinicalTrials.gov registry entry for NCT03300726 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,296-participant average among 7 other Alzheimer Disease, Late Onset trials with a reported enrollment target (98% lower). The listed sponsor is Ohio State University, which has 552 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Alzheimer Disease, Late Onset appearing as the primary indexed condition, and to 2 interventions - of which CSF analysis is the first listed.

NCT03300726 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT03300726 about?

NCT03300726 is a clinical study titled "Synaptic Injury and Functional Connectivity in Alzheimer's Disease". The purpose of this study is to examine cross-sectional associations between CSF markers of synaptic injury (Ng and SNAP-25) and functional connectivity in default and semantic memory networks using 3T- fMRI in individuals with MCI (i.e. the earliest clinically detectable stage of cognitive impairme...

What is the current status of trial NCT03300726?

This trial is currently completed. The enrollment target is 35 participants. The study started on 2018-02-12. Estimated completion is 2021-09-22.

What conditions does trial NCT03300726 study?

This clinical trial studies the following conditions: Alzheimer Disease, Late Onset.

What interventions are being tested in trial NCT03300726?

The interventions under investigation include: CSF analysis (DIAGNOSTIC_TEST), Functional MRI (RADIATION).

Who is sponsoring clinical trial NCT03300726?

This trial is sponsored by Ohio State University, which has 552 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03300726 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.