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NCT03281889 · ClinicalTrials.gov registry record · NA
Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation
A NA study of Brain Tumor, sponsored by Massachusetts General Hospital.
- Active
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 2
- Study locations
NCT03281889: Active NA study of Brain Tumor, sponsored by Massachusetts General Hospital.
NCT03281889 is a NA study of Brain Tumor that is active but no longer recruiting, run by Massachusetts General Hospital. The registered enrollment target is 20 participants, below the 281-participant average among 69 other Brain Tumor trials with a reported enrollment target (93% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03281889, a NA study of Brain Tumor, is active but no longer recruiting, sponsored by Massachusetts General Hospital.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 2
- Study locations
Study Summary
This research study is studying proton radiation as a possible treatment for brain tumor that requires radiation. The radiation involved in this study is: -Proton Radiation
Primary Outcome
IMPT using PBS delivery will be considered to be feasible as a VBS technique for CSI in pediatric patients if the rate of grade 3/4 hematologic toxicity were no more than 5% within 3 months after the completion of radiation treatment, within the range associated with conventional techniques of CSI. Toxicity will be assess using Common Terminology Criteria for Adverse Events (CTCAE) Version 4.0.
Conditions Studied
Interventions
- RADIATION Proton Beam
Study Locations (2)
Massachusetts
- Massachusetts General Hospital - Boston
Texas
- MD Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2018-01-04 |
| Est. Completion | 2027-12-31 |
| Phase | NA |
What the registry record for NCT03281889 still lists
NCT03281889 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 281-participant average among 69 other Brain Tumor trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Brain Tumor appearing as the primary indexed condition, and to 1 intervention - of which Proton Beam is the first listed.
NCT03281889 reports a single indexed study location in Massachusetts, Texas.
Frequently Asked Questions
What is clinical trial NCT03281889 about?
NCT03281889 is a clinical study titled "Proton Craniospinal Irradiation With Bone Sparing to Decrease Growth Decrement From Radiation". This research study is studying proton radiation as a possible treatment for brain tumor that requires radiation. The radiation involved in this study is: -Proton Radiation
What is the current status of trial NCT03281889?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2018-01-04. Estimated completion is 2027-12-31.
What conditions does trial NCT03281889 study?
This clinical trial studies the following conditions: Brain Tumor.
What interventions are being tested in trial NCT03281889?
The interventions under investigation include: Proton Beam (RADIATION).
Who is sponsoring clinical trial NCT03281889?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03281889 being conducted?
This trial has 2 study locations across Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Brain Tumor
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03281889's enrollment target sits among peer trials
20 57th of 69 higher than 12 of 69 other Brain Tumor trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Brain Tumor trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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