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NCT03267914 · ClinicalTrials.gov registry record · NA

Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy

A NA study of Dental Caries and Oral Cavity Cancer, sponsored by A.T. Still University of Health Sciences.

Completed
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT03267914: Completed NA study of Dental Caries and Oral Cavity Cancer, sponsored by A.T. Still University of Health Sciences.

NCT03267914 is a NA study of Dental Caries and Oral Cavity Cancer that has completed, run by A.T. Still University of Health Sciences. The registered enrollment target is 20 participants, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03267914, a NA study of Dental Caries and Oral Cavity Cancer, has completed, sponsored by A.T. Still University of Health Sciences.

COMPLETED
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Approximately 40 people will participate in this study. This study will compare two different methods of fluoride application. Both methods are currently used in dental practice and both have been shown to be effective. If the participant chooses to participate in this study, participant will be asked to either wear a small tray that has been custom made to fit into the mouth into which fluoride is placed and worn for 5 minutes at bedtime, or participant will be asked to brush fluoride onto the teeth for 2 minutes at bedtime. Participant will be randomly assigned to use one of these methods of fluoride application: participant will not be allowed to choose which method of application you prefer. Participant will be asked to use fluoride every night while enrolled in the study. The fluoride that is used in the study is approved by the United States Food and Drug Administration and is commercially available with a prescription. After the study is over, participant will need to continue to use fluoride every night for life to help reduce the risk for dental cavities in the future. During the study, participant will receive a dental examination every 3 months for a total of 4 study visits over the period of 1 year. This visit will consist of a dental examination to identify any new cavities and instructions for fluoride use. Participant will also be asked to complete a written log to document daily fluoride use and to give feedback about compliance with fluoride use.

Primary Outcome

To evaluate compliance, subjects will be asked about their fluoride use according to methods described by Epstein et al. (1996). High compliance is defined as daily use; low compliance is defined as two to three times per week; not compliant is defined as less than two times per week.

Interventions

  • OTHER Tray
  • OTHER Brush

Study Locations (1)

Arizona

  • A.T. Still University, Arizona School of Dentistry & Oral Health - Mesa

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2017-08-29
Est. Completion 2021-11-22
Phase NA

What the finished NCT03267914 record still lists

NCT03267914 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (97% lower).

The record links to 3 conditions, with Dental Caries appearing as the primary indexed condition, and to 2 interventions - of which Tray is the first listed.

NCT03267914 reports a single indexed study location in Arizona.

Frequently Asked Questions

What is clinical trial NCT03267914 about?

NCT03267914 is a clinical study titled "Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy". Approximately 40 people will participate in this study. This study will compare two different methods of fluoride application. Both methods are currently used in dental practice and both have been shown to be effective. If the participant chooses to participate in this study, participant will be ask...

What is the current status of trial NCT03267914?

This trial is currently completed. It is a NA study. The enrollment target is 20 participants. The study started on 2017-08-29. Estimated completion is 2021-11-22.

What conditions does trial NCT03267914 study?

This clinical trial studies the following conditions: Dental Caries, Oral Cavity Cancer, Oral Complications of Chemotherapy and Head/Neck Radiation.

What interventions are being tested in trial NCT03267914?

The interventions under investigation include: Tray (OTHER), Brush (OTHER).

Who is sponsoring clinical trial NCT03267914?

This trial is sponsored by A.T. Still University of Health Sciences, which has 16 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03267914 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Dental Caries

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03267914's enrollment target sits among peer trials

20 28th of 30 higher than 2 of 30 other Dental Caries trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Dental Caries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03267914, the US trial registry maintained by the National Library of Medicine. NCT03267914 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.