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NCT03192436 · ClinicalTrials.gov registry record · NA

Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound

A NA study of Healthy, sponsored by Carnegie Mellon University.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT03192436: Recruiting NA study of Healthy, sponsored by Carnegie Mellon University.

NCT03192436 is a NA study of Healthy that is actively recruiting participants, run by Carnegie Mellon University. The registered enrollment target is 80 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03192436, a NA study of Healthy, is actively recruiting participants, sponsored by Carnegie Mellon University.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

Neuromodulation is a fast growing field that offers a wide range of applications for both understanding and treating the brain. Future research for non-invasive neuromodulation will need to elucidate the optimal frequency, duration, and intensity of stimulation for a variety of technologies and diseases. Closed loop stimulation is thus a promising research area that allows for responsive stimulation and real time symptom management. Our project is proposed to develop and test a novel noninvasive neuromodulation integrating transcranial focused ultrasound stimulation (tFUS) with electrophysiological source imaging (ESI-tFUS) to allow evidence-based neuromodulation for brain research and the management of brain conditions. Despite the recent developments and attention surrounding tFUS, relatively little is known about the mechanisms and optimal parameters of this stimulation technology. The addition of ESI neuroimaging, aimed at providing biomarkers to assess the effects of tFUS neuromodulation, could provide crucial necessary information regarding the neural response to the applied stimulation in real-time. In order for tFUS to be further developed and transformed into a robust neuromodulation technology, an integrated electrophysiological source-imaging-guided tFUS system to allow for individualized and responsive stimulation is needed. The purpose of this study is to develop and evaluate the proposed ESI-tFUS in human subjects using motor and somatosensory paradigms.

Conditions Studied

Healthy

Interventions

  • DEVICE Ultrasound

Study Locations (1)

Pennsylvania

  • Department of Biomedical Engineering, Carnegie Mellon University - Pittsburgh

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2018-09-01
Est. Completion 2030-06-30
Phase NA

Sponsor

Carnegie Mellon University

37 total trials

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What the Registry Record Tells You About NCT03192436

The ClinicalTrials.gov registry entry for NCT03192436 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (88% lower). The listed sponsor is Carnegie Mellon University, which has 37 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Ultrasound is the first listed.

NCT03192436 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT03192436 about?

NCT03192436 is a clinical study titled "Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound". Neuromodulation is a fast growing field that offers a wide range of applications for both understanding and treating the brain. Future research for non-invasive neuromodulation will need to elucidate the optimal frequency, duration, and intensity of stimulation for a variety of technologies and dise...

What is the current status of trial NCT03192436?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2018-09-01. Estimated completion is 2030-06-30.

What conditions does trial NCT03192436 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT03192436?

The interventions under investigation include: Ultrasound (DEVICE).

Who is sponsoring clinical trial NCT03192436?

This trial is sponsored by Carnegie Mellon University, which has 37 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03192436 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Read our methodology - how this data is sourced, computed, and verified.
Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.