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NCT03151564 · ClinicalTrials.gov registry record · NA

Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques

A NA study of Colorectal Carcinoma and Liver Metastases, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
NA
Development phase
146
Enrollment target
1
Study location

NCT03151564: Active NA study of Colorectal Carcinoma and Liver Metastases, sponsored by M.D. Anderson Cancer Center.

NCT03151564 is a NA study of Colorectal Carcinoma and Liver Metastases that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 146 participants, below the 1,094-participant average among 53 other Colorectal Carcinoma trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03151564, a NA study of Colorectal Carcinoma and Liver Metastases, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
146 participants
Enrollment target
1
Study location

Study Summary

To compare 2 different image creation/processing techniques during a standard CT scan in order to "see" problems in the liver and learn which method provides better image quality. The techniques use new artificial intelligence software to decrease image noise, which helps the radiologist to evaluate.

Primary Outcome

Primary endpoint is metastasis detection accuracy status of each patient, where the standard of care scan reviewed by ''truth readers'' (independent to the blinded radiologists) serve as the gold standard. If any lesion of a patient is diagnosed as metastasis by "truth readers" or blinded readers' consensus, that patient will be considered true positive and diagnosis positive, respectively. The expected accuracy of standard CT is 95%, and a low dose CT detection be considered non-inferior if its

Interventions

  • DIAGNOSTIC_TEST Computed Tomography Scan - 50% Dose Reduction
  • DIAGNOSTIC_TEST Computed Tomography Scan - 70% Dose Reduction
  • DIAGNOSTIC_TEST Deep Learning Image Reconstruction (DLIR)

Study Locations (1)

Texas

  • University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 146 participants
Start Date 2017-05-09
Est. Completion 2027-04-30
Phase NA
M.D. Anderson Cancer Center

2,692 total trials

What the registry record for NCT03151564 still lists

NCT03151564 is an interventional study that assigns participants to a tested intervention. The registered 146 participants enrollment target is mid-sized for trials with a published cap, below the 1,094-participant average among 53 other Colorectal Carcinoma trials with a reported enrollment target (87% lower).

The record links to 4 conditions, with Colorectal Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Computed Tomography Scan - 50% Dose Reduction is the first listed.

NCT03151564 reports a single indexed study location in Texas.

Frequently Asked Questions

What is clinical trial NCT03151564 about?

NCT03151564 is a clinical study titled "Lesion Detection Assessment in the Liver: Standard vs Low Radiation Dose Using Varied Post-Processing Techniques". To compare 2 different image creation/processing techniques during a standard CT scan in order to "see" problems in the liver and learn which method provides better image quality. The techniques use new artificial intelligence software to decrease image noise, which helps the radiologist to evaluate...

What is the current status of trial NCT03151564?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 146 participants. The study started on 2017-05-09. Estimated completion is 2027-04-30.

What conditions does trial NCT03151564 study?

This clinical trial studies the following conditions: Colorectal Carcinoma, Liver Metastases, Colon Carcinoma, Diseases of Liver.

What interventions are being tested in trial NCT03151564?

The interventions under investigation include: Computed Tomography Scan - 50% Dose Reduction (DIAGNOSTIC_TEST), Computed Tomography Scan - 70% Dose Reduction (DIAGNOSTIC_TEST), Deep Learning Image Reconstruction (DLIR) (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03151564?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03151564 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Colorectal Carcinoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT03151564's enrollment target sits among peer trials

146 22nd of 53 higher than 32 of 53 other Colorectal Carcinoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Colorectal Carcinoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT03151564, the US trial registry maintained by the National Library of Medicine. NCT03151564 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.