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NCT03142893 · ClinicalTrials.gov registry record · Phase 1
Hormonal Mechanisms of Sleep Restriction - Axis Study
A Phase 1 study of Sleep Restriction, sponsored by Peter y. Liu.
- Active
- Registry status
- Phase 1
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT03142893: Active Phase 1 study of Sleep Restriction, sponsored by Peter y. Liu.
NCT03142893 is a Phase 1 study of Sleep Restriction that is active but no longer recruiting, run by Peter y. Liu. The registered enrollment target is 80 participants, above the 47-participant average among 4 other Sleep Restriction trials with a reported enrollment target (70% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03142893, a Phase 1 study of Sleep Restriction, is active but no longer recruiting, sponsored by Peter y. Liu.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with sleep restriction. The investigator will also examine the cognitive function associated with sleep restriction, including food intake and food cravings.
Primary Outcome
Cortisol is measured in blood every 10 minutes for a 5 hour period, at the beginning and at the end of 4 nights of sleep restriction. The average cortisol is the parameter of interest.
Conditions Studied
Interventions
- DRUG Dexamethasone
- DRUG Ketoconazole Pill
- DRUG Ganirelix
- DRUG Dexamethasone Injection
- DRUG Cosyntropin Injectable Product
Study Locations (1)
California
- Los Angeles Biomedical Research Institute - Torrance
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2017-05-08 |
| Est. Completion | 2026-06-30 |
| Phase | Phase 1 |
What the registry record for NCT03142893 still lists
NCT03142893 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 47-participant average among 4 other Sleep Restriction trials with a reported enrollment target (70% higher).
The record links to 1 condition, with Sleep Restriction appearing as the primary indexed condition, and to 5 interventions - of which Dexamethasone is the first listed.
NCT03142893 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03142893 about?
NCT03142893 is a clinical study titled "Hormonal Mechanisms of Sleep Restriction - Axis Study". The purpose of this study is to 1) determine how hypothalamic-pituitary-adrenal axis (HPA axis) activation occurs with sleep restriction 2) evaluate how hypothalamic-pituitary-gonadal axis (HPG axis) deactivation occurs with sleep restriction. The investigator will also examine the cognitive functio...
What is the current status of trial NCT03142893?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 80 participants. The study started on 2017-05-08. Estimated completion is 2026-06-30.
What conditions does trial NCT03142893 study?
This clinical trial studies the following conditions: Sleep Restriction.
What interventions are being tested in trial NCT03142893?
The interventions under investigation include: Dexamethasone (DRUG), Ketoconazole Pill (DRUG), Ganirelix (DRUG), Dexamethasone Injection (DRUG), Cosyntropin Injectable Product (DRUG).
Who is sponsoring clinical trial NCT03142893?
This trial is sponsored by Peter y. Liu, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03142893 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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