Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT03115333 · ClinicalTrials.gov registry record · NA

DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma

A NA study of Recurrent Glioblastoma and Gliosarcoma, sponsored by ECOG-ACRIN Cancer Research Group.

Active
Registry status
NA
Development phase
146
Enrollment target
20
Study locations

NCT03115333 is a NA study of Recurrent Glioblastoma and Gliosarcoma that is active but no longer recruiting, run by ECOG-ACRIN Cancer Research Group. The registered enrollment target is 146 participants, above the 67-participant average among 62 other Recurrent Glioblastoma trials with a reported enrollment target (118% higher). The trial reports 20 study locations across 6 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT03115333, a NA study of Recurrent Glioblastoma and Gliosarcoma, is active but no longer recruiting, sponsored by ECOG-ACRIN Cancer Research Group.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
146 participants
Enrollment target
20
Study locations

Study Summary

This phase II trial studies how well dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI) works in measuring relative cerebral blood volume (rCBV) for early response to bevacizumab in patients with glioblastoma that has come back. DSC-MRI may help evaluate changes in the blood vessels within the cancer to determine a patient?s response to treatment.

Interventions

  • DIAGNOSTIC_TEST Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging

Study Locations (20)

Florida

  • Boca Raton Regional Hospital - Boca Raton
  • Baptist MD Anderson Cancer Center - Jacksonville
  • Mayo Clinic in Florida - Jacksonville
  • Moffitt Cancer Center-International Plaza - Tampa
  • Moffitt Cancer Center - McKinley Campus - Tampa
  • Moffitt Cancer Center - Tampa

California

  • Eden Hospital Medical Center - Castro Valley
  • Loma Linda University Medical Center - Loma Linda
  • USC / Norris Comprehensive Cancer Center - Los Angeles
  • UC Irvine Health/Chao Family Comprehensive Cancer Center - Orange
  • VA Palo Alto Health Care System - Palo Alto

Arizona

  • Saint Joseph's Hospital and Medical Center - Phoenix
  • Mayo Clinic Hospital - Phoenix
  • Mayo Clinic in Arizona - Scottsdale

Georgia

  • Emory University Hospital/Winship Cancer Institute - Atlanta
  • Northside Hospital - Atlanta
  • Northside Hospital-Forsyth - Cumming

Indiana

  • Indiana University/Melvin and Bren Simon Cancer Center - Indianapolis
  • IU Health Methodist Hospital - Indianapolis

Kentucky

  • Baptist Health Lexington - Lexington

Trial Details

FieldValue
Enrollment Target 146 participants
Start Date 2017-07-25
Est. Completion 2027-05-07
Phase NA

Sponsor

ECOG-ACRIN Cancer Research Group

75 total trials

What the Registry Record Tells You About NCT03115333

The ClinicalTrials.gov registry entry for NCT03115333 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 146 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 67-participant average among 62 other Recurrent Glioblastoma trials with a reported enrollment target (118% higher). The listed sponsor is ECOG-ACRIN Cancer Research Group, which has 75 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Recurrent Glioblastoma appearing as the primary indexed condition, and to 1 intervention - of which Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging is the first listed.

NCT03115333 reports 20 study locations spanning 6 distinct geographic areas - top geographies include Florida, California, Arizona.

Frequently Asked Questions

What is clinical trial NCT03115333 about?

NCT03115333 is a clinical study titled "DSC-MRI in Measuring rCBV for Early Response to Bevacizumab in Patients With Recurrent Glioblastoma". This phase II trial studies how well dynamic susceptibility contrast-enhanced magnetic resonance imaging (DSC-MRI) works in measuring relative cerebral blood volume (rCBV) for early response to bevacizumab in patients with glioblastoma that has come back. DSC-MRI may help evaluate changes in the blo...

What is the current status of trial NCT03115333?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 146 participants. The study started on 2017-07-25. Estimated completion is 2027-05-07.

What conditions does trial NCT03115333 study?

This clinical trial studies the following conditions: Recurrent Glioblastoma, Gliosarcoma.

What interventions are being tested in trial NCT03115333?

The interventions under investigation include: Dynamic Susceptibility Contrast-Enhanced Magnetic Resonance Imaging (DIAGNOSTIC_TEST).

Who is sponsoring clinical trial NCT03115333?

This trial is sponsored by ECOG-ACRIN Cancer Research Group, which has 75 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03115333 being conducted?

This trial has 20 study locations across Arizona, California, Florida, Georgia, Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Recurrent Glioblastoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.