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NCT03085433 · ClinicalTrials.gov registry record · NA
Sperm Selection by Microfluidic Separation Improves Embryo Quality
A NA study of Infertility and Infertility, Male, sponsored by University of California, San Francisco.
- Completed
- Registry status
- NA
- Development phase
- 393
- Enrollment target
- 1
- Study location
NCT03085433: Completed NA study of Infertility and Infertility, Male, sponsored by University of California, San Francisco.
NCT03085433 is a NA study of Infertility and Infertility, Male that has completed, run by University of California, San Francisco. The registered enrollment target is 393 participants, below the 7,584-participant average among 74 other Infertility trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03085433, a NA study of Infertility and Infertility, Male, has completed, sponsored by University of California, San Francisco.
- COMPLETED
- Registry status
- NA
- Development phase
- 393 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a randomized controlled trial of couples with a history of poor embryo quality undergoing a repeat in vitro fertilization (IVF) cycle for unexplained infertility. Couples will be randomized to sperm selection by the clinical standard of centrifugation and density-gradient processing compared to the microfluidic sperm sorting chip.
Primary Outcome
The primary outcome for intent to treat analysis. Day 3 high quality embryo percentage rate will be defined as the percentage of all viable 2PN embryos on day 3 with at least 6 cells and fragmentation/symmetry scores of 1-2. Scale: 1-6 for either fragmentation or symmetry. Lower scores are better. Calculated as ( the number of high-qualify-grade embryos yielded by a participant / the number of all viable 2PN embryos yielded by the participant x 100)
Conditions Studied
Interventions
- DEVICE Microfluidic Sperm Sorting
- PROCEDURE in vitro fertilization
Study Locations (1)
California
- University of California San Francisco - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 393 participants |
| Start Date | 2017-06-20 |
| Est. Completion | 2022-04-30 |
| Phase | NA |
What the finished NCT03085433 record still lists
NCT03085433 is an interventional study that assigns participants to a tested intervention. The registered 393 participants enrollment target is mid-sized for trials with a published cap, below the 7,584-participant average among 74 other Infertility trials with a reported enrollment target (95% lower).
The record links to 6 conditions, with Infertility appearing as the primary indexed condition, and to 2 interventions - of which Microfluidic Sperm Sorting is the first listed.
NCT03085433 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT03085433 about?
NCT03085433 is a clinical study titled "Sperm Selection by Microfluidic Separation Improves Embryo Quality". This is a randomized controlled trial of couples with a history of poor embryo quality undergoing a repeat in vitro fertilization (IVF) cycle for unexplained infertility. Couples will be randomized to sperm selection by the clinical standard of centrifugation and density-gradient processing compared...
What is the current status of trial NCT03085433?
This trial is currently completed. It is a NA study. The enrollment target is 393 participants. The study started on 2017-06-20. Estimated completion is 2022-04-30.
What conditions does trial NCT03085433 study?
This clinical trial studies the following conditions: Infertility, Infertility, Male, Fertility Disorders, Sperm DNA Fragmentation, Infertility Unexplained.
What interventions are being tested in trial NCT03085433?
The interventions under investigation include: Microfluidic Sperm Sorting (DEVICE), in vitro fertilization (PROCEDURE).
Who is sponsoring clinical trial NCT03085433?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03085433 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT03085433's enrollment target sits among peer trials
393 29th of 74 higher than 46 of 74 other Infertility trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Infertility trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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