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NCT07225660 · ClinicalTrials.gov registry record · NA
Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)
A NA study of Fertility Preservation, sponsored by Shady Grove Fertility Reproductive Science Center.
- Recruiting
- Registry status
- NA
- Development phase
- 394
- Enrollment target
- 3
- Study locations
NCT07225660: Recruiting NA study of Fertility Preservation, sponsored by Shady Grove Fertility Reproductive Science Center.
NCT07225660 is a NA study of Fertility Preservation that is actively recruiting participants, run by Shady Grove Fertility Reproductive Science Center. The registered enrollment target is 394 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07225660, a NA study of Fertility Preservation, is actively recruiting participants, sponsored by Shady Grove Fertility Reproductive Science Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 394 participants
- Enrollment target
- 3
- Study locations
Study Summary
HOLIDAY is a two-arm, parallel-group, multi-center, randomized trial in which subjects undergoing planned oocyte cryopreservation will be randomized to receive either a 2-month pause of Combined Hormonal Contraceptives (CHC) or immediate start (without a pause).
Primary Outcome
Median number of percentage of vitrified MII oocytes yielded per cycle
Conditions Studied
Interventions
- OTHER OCP pause
Study Locations (3)
Connecticut
- Yale Fertility Center - Orange
Maryland
- Shady Grove Fertility Rockville - Rockville
New York
- Reproductive Medicine Associates of New York - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 394 participants |
| Start Date | 2026-02-25 |
| Est. Completion | 2027-07-01 |
| Phase | NA |
What NCT07225660 shows while recruiting
NCT07225660 is an interventional study that assigns participants to a tested intervention. The registered 394 participants enrollment target is mid-sized for trials with a published cap, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (72% lower).
The record links to 1 condition, with Fertility Preservation appearing as the primary indexed condition, and to 1 intervention - of which OCP pause is the first listed.
NCT07225660 reports a single indexed study location in Connecticut, Maryland, New York.
Frequently Asked Questions
What is clinical trial NCT07225660 about?
NCT07225660 is a clinical study titled "Hormonal Optimization: Late vs. Immediate Start After Discontinuation of Oral Contraceptives in Assisted Reproductive technologY (HOLIDAY)". HOLIDAY is a two-arm, parallel-group, multi-center, randomized trial in which subjects undergoing planned oocyte cryopreservation will be randomized to receive either a 2-month pause of Combined Hormonal Contraceptives (CHC) or immediate start (without a pause).
What is the current status of trial NCT07225660?
This trial is currently recruiting. It is a NA study. The enrollment target is 394 participants. The study started on 2026-02-25. Estimated completion is 2027-07-01.
What conditions does trial NCT07225660 study?
This clinical trial studies the following conditions: Fertility Preservation.
What interventions are being tested in trial NCT07225660?
The interventions under investigation include: OCP pause (OTHER).
Who is sponsoring clinical trial NCT07225660?
This trial is sponsored by Shady Grove Fertility Reproductive Science Center, which has 6 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07225660 being conducted?
This trial has 3 study locations across Connecticut, Maryland, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Fertility Preservation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07225660's enrollment target sits among peer trials
394 268th of 2000 higher than 1,733 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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