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NCT03069378 · ClinicalTrials.gov registry record · Phase 2

A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma

A Phase 2 study of Sarcoma and Epithelioid Sarcoma, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Phase 2
Development phase
41
Enrollment target
5
Study locations

NCT03069378 is a Phase 2 study of Sarcoma and Epithelioid Sarcoma that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 41 participants, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (96% lower). The trial reports 5 study locations across 3 states.

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The verdict

NCT03069378, a Phase 2 study of Sarcoma and Epithelioid Sarcoma, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
41 participants
Enrollment target
5
Study locations

Study Summary

The purpose of this study is to determine how well the combination of therapy of talimogene laherparepvec (T-VEC) and pembrolizumab works in the treatment of patients with sarcoma.

Interventions

  • DRUG Pembrolizumab
  • DRUG Talimogene Laherparepvec (T-VEC)

Study Locations (5)

California

  • Enable Medicine (Specimen Analysis Only) - Menlo Park
  • Stanford University Medical Center - Stanford

New York

  • Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
  • Memorial Sloan Kettering Cancer Center - New York

Texas

  • MD Anderson Cancer Center (Data Analysis Only) - Houston

Trial Details

FieldValue
Enrollment Target 41 participants
Start Date 2017-03-03
Est. Completion 2026-03
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT03069378

The ClinicalTrials.gov registry entry for NCT03069378 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 41 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (96% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Sarcoma appearing as the primary indexed condition, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT03069378 reports 5 study locations spanning 3 distinct geographic areas - top geographies include California, New York, Texas.

Frequently Asked Questions

What is clinical trial NCT03069378 about?

NCT03069378 is a clinical study titled "A Study of Talimogene Laherparepvec (T-VEC) in Combination With Pembrolizumab in Patients With Metastatic and/or Locally Advanced Sarcoma". The purpose of this study is to determine how well the combination of therapy of talimogene laherparepvec (T-VEC) and pembrolizumab works in the treatment of patients with sarcoma.

What is the current status of trial NCT03069378?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 2017-03-03. Estimated completion is 2026-03.

What conditions does trial NCT03069378 study?

This clinical trial studies the following conditions: Sarcoma, Epithelioid Sarcoma, Cutaneous Angiosarcoma.

What interventions are being tested in trial NCT03069378?

The interventions under investigation include: Pembrolizumab (DRUG), Talimogene Laherparepvec (T-VEC) (DRUG).

Who is sponsoring clinical trial NCT03069378?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03069378 being conducted?

This trial has 5 study locations across California, New York, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.