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NCT02997176 · ClinicalTrials.gov registry record · Phase 1

An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800)

A Phase 1 study of Advanced Solid Tumors, sponsored by Pfizer.

Completed
Registry status
Phase 1
Development phase
38
Enrollment target
11
Study locations

NCT02997176 is a Phase 1 study of Advanced Solid Tumors that has completed, run by Pfizer. The registered enrollment target is 38 participants, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (81% lower). The trial reports 11 study locations across 3 states.

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The verdict

NCT02997176, a Phase 1 study of Advanced Solid Tumors, has completed, sponsored by Pfizer.

COMPLETED
Registry status
Phase 1
Development phase
38 participants
Enrollment target
11
Study locations

Study Summary

This is a trial to investigate the pharmacokinetics (PK) and the safety of talazoparib in patients with advanced solid tumors and impaired hepatic function.

Conditions Studied

Interventions

  • DRUG Talazoparib

Study Locations (11)

California

  • UCLA Hematology/Oncology - Alhambra - Alhambra
  • CBCC Global Research, Inc. at Comprehensive Blood and Cancer Center - Bakersfield
  • St. Joseph Heritage Healthcare - Fullerton
  • St. Jude Hospital Yorba Linda DBA St. Joseph Heritage Healthcare - Fullerton
  • UCLA Hematology/Oncology - Los Angeles
  • UCLA Hematology/Oncology - Porter Ranch - Porter Ranch
  • UCLA Hematology/Oncology - Santa Monica - Santa Monica
  • UCLA Torrance Oncology - Torrance
  • UCLA Hematology/Oncology - Santa Clarita - Valencia

Florida

  • Orlando Health, Inc. - Orlando

Texas

  • The University of Texas MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2016-09-30
Est. Completion 2020-02-12
Phase Phase 1

Sponsor

Pfizer

1,845 total trials

What the Registry Record Tells You About NCT02997176

The ClinicalTrials.gov registry entry for NCT02997176 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 198-participant average among 144 other Advanced Solid Tumors trials with a reported enrollment target (81% lower). The listed sponsor is Pfizer, which has 1,845 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Advanced Solid Tumors appearing as the primary indexed condition, and to 1 intervention - of which Talazoparib is the first listed.

NCT02997176 reports 11 study locations spanning 3 distinct geographic areas - top geographies include California, Florida, Texas.

Frequently Asked Questions

What is clinical trial NCT02997176 about?

NCT02997176 is a clinical study titled "An Open-Label Pharmacokinetics and Safety Study of Talazoparib (MDV3800)". This is a trial to investigate the pharmacokinetics (PK) and the safety of talazoparib in patients with advanced solid tumors and impaired hepatic function.

What is the current status of trial NCT02997176?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 38 participants. The study started on 2016-09-30. Estimated completion is 2020-02-12.

What conditions does trial NCT02997176 study?

This clinical trial studies the following conditions: Advanced Solid Tumors.

What interventions are being tested in trial NCT02997176?

The interventions under investigation include: Talazoparib (DRUG).

Who is sponsoring clinical trial NCT02997176?

This trial is sponsored by Pfizer, which has 1,845 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02997176 being conducted?

This trial has 11 study locations across California, Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.