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NCT02839837 · ClinicalTrials.gov registry record · NA
Acute Aerobic Exercise and Neuroplasticity in Depression
A NA study of Depression and Depressive Disorder, sponsored by Medical University of South Carolina.
- Completed
- Registry status
- NA
- Development phase
- 38
- Enrollment target
- 1
- Study location
NCT02839837: Completed NA study of Depression and Depressive Disorder, sponsored by Medical University of South Carolina.
NCT02839837 is a NA study of Depression and Depressive Disorder that has completed, run by Medical University of South Carolina. The registered enrollment target is 38 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02839837, a NA study of Depression and Depressive Disorder, has completed, sponsored by Medical University of South Carolina.
- COMPLETED
- Registry status
- NA
- Development phase
- 38 participants
- Enrollment target
- 1
- Study location
Study Summary
Depression is associated with a disruption in the mechanisms that regulate neuroplasticity. Effective treatment and rehabilitation of depression, and other neurological and neuropsychiatric disorders, relies on neuroplasticity. Thus, identifying therapies that enhance neuroplasticity (neuroplastic adaptation) are vital in the comprehensive treatment of depression. Aerobic exercise training has been demonstrated to have antidepressant properties and single bouts of aerobic exercise may provide short-term improvements in affective states in depression. Furthermore, acute aerobic exercise may enhance the response to known neuroplasticity-inducing paradigms. However, it is unclear if aerobic exercise can influence neuroplasticity in depression and the neurobiological mechanisms underlying acute neuroplastic changes are not well understood in depressed and healthy cohorts. Thus, the purpose of this project is to examine the acute effects of aerobic exercise on neuroplastic, neurobiological, and mood indices of depression.
Conditions Studied
Interventions
- BEHAVIORAL Aerobic Exercise
- DEVICE Paired Associative Stimulation
Study Locations (1)
South Carolina
- Stroke Recovery Research Center - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2016-05 |
| Est. Completion | 2018-12 |
| Phase | NA |
What the finished NCT02839837 record still lists
NCT02839837 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 38 participants, a relatively small participant target, below the 786-participant average among 679 other Depression trials with a reported enrollment target (95% lower).
The record links to 2 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Aerobic Exercise is the first listed.
NCT02839837 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT02839837 about?
NCT02839837 is a clinical study titled "Acute Aerobic Exercise and Neuroplasticity in Depression". Depression is associated with a disruption in the mechanisms that regulate neuroplasticity. Effective treatment and rehabilitation of depression, and other neurological and neuropsychiatric disorders, relies on neuroplasticity. Thus, identifying therapies that enhance neuroplasticity (neuroplastic a...
What is the current status of trial NCT02839837?
This trial is currently completed. It is a NA study. The enrollment target is 38 participants. The study started on 2016-05. Estimated completion is 2018-12.
What conditions does trial NCT02839837 study?
This clinical trial studies the following conditions: Depression, Depressive Disorder.
What interventions are being tested in trial NCT02839837?
The interventions under investigation include: Aerobic Exercise (BEHAVIORAL), Paired Associative Stimulation (DEVICE).
Who is sponsoring clinical trial NCT02839837?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02839837 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02839837's enrollment target sits among peer trials
38 531st of 679 higher than 146 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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