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NCT02708433 · ClinicalTrials.gov registry record · NA

Clinical Outcomes of Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine

A NA study of Anesthesia, sponsored by University of North Carolina, Chapel Hill.

Completed
Registry status
NA
Development phase
23
Enrollment target
1
Study location

NCT02708433: Completed NA study of Anesthesia, sponsored by University of North Carolina, Chapel Hill.

NCT02708433 is a NA study of Anesthesia that has completed, run by University of North Carolina, Chapel Hill. The registered enrollment target is 23 participants, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02708433, a NA study of Anesthesia, has completed, sponsored by University of North Carolina, Chapel Hill.

COMPLETED
Registry status
NA
Development phase
23 participants
Enrollment target
1
Study location

Study Summary

Anecdotal data suggest that the buffered form of the local anesthetic is more potent at equal dosages, and a lower dosage of the drug might be used with an effect equal to higher dosage not buffered. Clinical data are needed to confirm these anecdotal data. No data exist comparing buffered local anesthetics at lower drug concentrations to current dosages commonly used in dental and oral surgical procedures

Primary Outcome

Subject's Mandibular first molar teeth tested before anesthetic and every 30 minutes after for response to Cold and Electric Pulp Test as reported by subjects as a "yes" or "no."

Conditions Studied

Interventions

  • DRUG Lidocaine

Study Locations (1)

North Carolina

  • UNC School of Dentistry - Chapel Hill

Trial Details

FieldValue
Enrollment Target 23 participants
Start Date 2016-03
Est. Completion 2017-09
Phase NA

What the finished NCT02708433 record still lists

NCT02708433 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 109,410-participant average among 57 other Anesthesia trials with a reported enrollment target (100% lower).

The record links to 1 condition, with Anesthesia appearing as the primary indexed condition, and to 1 intervention - of which Lidocaine is the first listed.

NCT02708433 reports a single indexed study location in North Carolina.

Frequently Asked Questions

What is clinical trial NCT02708433 about?

NCT02708433 is a clinical study titled "Clinical Outcomes of Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine". Anecdotal data suggest that the buffered form of the local anesthetic is more potent at equal dosages, and a lower dosage of the drug might be used with an effect equal to higher dosage not buffered. Clinical data are needed to confirm these anecdotal data. No data exist comparing buffered local ane...

What is the current status of trial NCT02708433?

This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2016-03. Estimated completion is 2017-09.

What conditions does trial NCT02708433 study?

This clinical trial studies the following conditions: Anesthesia.

What interventions are being tested in trial NCT02708433?

The interventions under investigation include: Lidocaine (DRUG).

Who is sponsoring clinical trial NCT02708433?

This trial is sponsored by University of North Carolina, Chapel Hill, which has 1,109 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02708433 being conducted?

This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Anesthesia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02708433's enrollment target sits among peer trials

23 49th of 57 higher than 9 of 57 other Anesthesia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Anesthesia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02708433, the US trial registry maintained by the National Library of Medicine. NCT02708433 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.