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NCT02685735 · ClinicalTrials.gov registry record · Phase 4

Predicting, Understanding and Speeding Recovery After TKA

A Phase 4 study, sponsored by Wake Forest University Health Sciences.

Terminated
Registry status
Phase 4
Development phase
350
Enrollment target

NCT02685735: Clinical Trial Phase 4 study, sponsored by Wake Forest University Health Sciences.

NCT02685735 is a Phase 4 study that was terminated before completion, run by Wake Forest University Health Sciences. The registered enrollment target is 350 participants, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (32% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02685735, a Phase 4 study, was terminated before completion, sponsored by Wake Forest University Health Sciences.

TERMINATED
Registry status
Phase 4
Development phase
350 participants
Enrollment target

Study Summary

The objective of this research study is to better understand patterns of recovery after Total Knee Arthroplasty (TKA) amd Total Hip Replacement (THA). The study will evaluate how pain, activity and cognitive (i.e., thinking style) responses determine patterns of recovery, and the study will evaluate the efficacy of gabapentin versus placebo for improving recovery after surgery.

Primary Outcome

Daily pain intensity report for each subject was fitted using growth curve model with parameters of intercept (modeled initial pain) and slope of change in natural log of time, adjusted for prognostic predictors for gabapentin and placebo group separately. The daily pain intensity was the WORST pain (not the average pain) in the past 24 hr on a scale where 0 is no pain and 10 is worst imaginable pain. Values represent an intercept of modeled worst daily pain on the first day after hospital disc

Interventions

  • DRUG Placebo
  • DRUG Gabapentin

Trial Details

FieldValue
Enrollment Target 350 participants
Start Date 2016-06-02
Est. Completion 2022-02-09
Phase Phase 4
Wake Forest University Health Sciences

1,140 total trials

Why NCT02685735 stopped before completion

NCT02685735 is an interventional study that assigns participants to a tested intervention. The registered 350 participants enrollment target is mid-sized for trials with a published cap, below the 518-participant average among 9,235 other Phase 4 trials with a reported enrollment target (32% lower).

The record links to 0 conditions, and to 2 interventions - of which Placebo is the first listed.

NCT02685735 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02685735 about?

NCT02685735 is a clinical study titled "Predicting, Understanding and Speeding Recovery After TKA". The objective of this research study is to better understand patterns of recovery after Total Knee Arthroplasty (TKA) amd Total Hip Replacement (THA). The study will evaluate how pain, activity and cognitive (i.e., thinking style) responses determine patterns of recovery, and the study will evaluate...

What is the current status of trial NCT02685735?

This trial is currently terminated. It is a Phase 4 study. The enrollment target is 350 participants. The study started on 2016-06-02. Estimated completion is 2022-02-09.

What interventions are being tested in trial NCT02685735?

The interventions under investigation include: Placebo (DRUG), Gabapentin (DRUG).

Who is sponsoring clinical trial NCT02685735?

This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02685735's enrollment target sits among peer trials

350 231st of 2000 higher than 1,761 of 2,000 other Phase 4 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 4 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02685735, the US trial registry maintained by the National Library of Medicine. NCT02685735 (mid enrollment · none site footprint · terminated) retrieved and formatted by PlainTrial, see methodology.