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NCT02658279 · ClinicalTrials.gov registry record · NA

Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype

A NA study of Glioma and Recurrent Malignant Glioma, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
NA
Development phase
27
Enrollment target
16
Study locations

NCT02658279 is a NA study of Glioma and Recurrent Malignant Glioma that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 27 participants, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (87% lower). The trial reports 16 study locations across 8 states.

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The verdict

NCT02658279, a NA study of Glioma and Recurrent Malignant Glioma, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
27 participants
Enrollment target
16
Study locations

Study Summary

The purpose of this study is to test if the study drug called pembrolizumab could control the growth or shrink the cancer but it could also cause side effects. Researchers hope to learn if the study drug will shrink the cancer by half, or prevent it from growing for at least 6 months. Pembrolizumab is an antibody that targets the immune system and activates it to stop cancer growth and/or kill cancer cells.

Interventions

  • DRUG Pembrolizumab

Study Locations (16)

New York

  • Memorial Sloan Kettering Commack - Commack
  • Memorial Sloan Kettering Westchester - Harrison
  • Memorial Sloan Kettering Cancer Center - New York
  • Memorial Sloan Kettering Nassau - Uniondale

Massachusetts

  • Massachusetts General Hospital - Boston
  • Brigham and Women's Hospital - Boston
  • Dana Farber Cancer Institute - Boston

New Jersey

  • Memorial Sloan Kettering Cancer Center - Basking Ridge
  • Memorial Sloan Kettering Monmouth - Middletown
  • Memorial Sloan Kettering Bergen - Montvale

California

  • University of California, Los Angeles - Los Angeles
  • University of California San Francisco - San Francisco

Florida

  • University of Miami - Miami

Ohio

  • Cleveland Clinic - Cleveland

Texas

  • Md Anderson Cancer Center - Houston

Utah

  • University of Utah - Salt Lake City

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2016-01-22
Est. Completion 2027-01
Phase NA

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT02658279

The ClinicalTrials.gov registry entry for NCT02658279 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 27 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 210-participant average among 87 other Glioma trials with a reported enrollment target (87% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Glioma appearing as the primary indexed condition, and to 1 intervention - of which Pembrolizumab is the first listed.

NCT02658279 reports 16 study locations spanning 8 distinct geographic areas - top geographies include New York, Massachusetts, New Jersey.

Frequently Asked Questions

What is clinical trial NCT02658279 about?

NCT02658279 is a clinical study titled "Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype". The purpose of this study is to test if the study drug called pembrolizumab could control the growth or shrink the cancer but it could also cause side effects. Researchers hope to learn if the study drug will shrink the cancer by half, or prevent it from growing for at least 6 months. Pembrolizumab ...

What is the current status of trial NCT02658279?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 27 participants. The study started on 2016-01-22. Estimated completion is 2027-01.

What conditions does trial NCT02658279 study?

This clinical trial studies the following conditions: Glioma, Recurrent Malignant Glioma.

What interventions are being tested in trial NCT02658279?

The interventions under investigation include: Pembrolizumab (DRUG).

Who is sponsoring clinical trial NCT02658279?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02658279 being conducted?

This trial has 16 study locations across California, Florida, Massachusetts, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.