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NCT02626000 · ClinicalTrials.gov registry record · Phase 1

Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY232 / KEYNOTE-137)

A Phase 1 study, sponsored by Amgen.

Completed
Registry status
Phase 1
Development phase
36
Enrollment target

NCT02626000 is a Phase 1 study that has completed, run by Amgen. The registered enrollment target is 36 participants.

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The verdict

NCT02626000, a Phase 1 study, has completed, sponsored by Amgen.

COMPLETED
Registry status
Phase 1
Development phase
36 participants
Enrollment target

Study Summary

The primary objective of this study was to evaluate the safety, as assessed by incidence of dose limiting toxicity (DLT), of talimogene laherparepvec in combination with pembrolizumab in adults with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN).

Interventions

  • BIOLOGICAL Pembrolizumab
  • DRUG Talimogene Laherparepvec

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2016-04-06
Est. Completion 2020-08-28
Phase Phase 1

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT02626000

The ClinicalTrials.gov registry entry for NCT02626000 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 36 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT02626000 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02626000 about?

NCT02626000 is a clinical study titled "Talimogene Laherparepvec With Pembrolizumab for Recurrent Metastatic Squamous Cell Carcinoma of the Head and Neck (MASTERKEY232 / KEYNOTE-137)". The primary objective of this study was to evaluate the safety, as assessed by incidence of dose limiting toxicity (DLT), of talimogene laherparepvec in combination with pembrolizumab in adults with recurrent or metastatic squamous cell carcinoma of the head and neck (SCCHN).

What is the current status of trial NCT02626000?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2016-04-06. Estimated completion is 2020-08-28.

What interventions are being tested in trial NCT02626000?

The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Talimogene Laherparepvec (DRUG).

Who is sponsoring clinical trial NCT02626000?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.