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NCT02575027 · ClinicalTrials.gov registry record · NA

Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme

A NA study of Glioblastoma and Recurrent Brain Neoplasm, sponsored by Jonsson Comprehensive Cancer Center.

Completed
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT02575027: Completed NA study of Glioblastoma and Recurrent Brain Neoplasm, sponsored by Jonsson Comprehensive Cancer Center.

NCT02575027 is a NA study of Glioblastoma and Recurrent Brain Neoplasm that has completed, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 10 participants, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02575027, a NA study of Glioblastoma and Recurrent Brain Neoplasm, has completed, sponsored by Jonsson Comprehensive Cancer Center.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

This pilot clinical trial studies the feasibility of palliative 4pi radiotherapy in treating patients with glioblastoma multiforme that has come back after standard chemoradiation. A new radiotherapy delivery planning system, called 4pi radiotherapy, may help improve radiation delivery by improving dose coverage to the treatment target, while reducing the dose to surrounding normal tissues.

Primary Outcome

The accuracy of dose delivery by 4pi will be compared to standard procedures. Standard quality assurance (QA) procedures will be employed to validate the delivery accuracy of 4pi. Specifically, a MatriXX phantom will be employed to measure the dose in both the coronal and sagittal planes and compared to calculation. Patients with QA results showing gamma passing rates (using 3% and 3 mm dose difference and distance to agreement criteria, respectively) less than 90% in either plane or a maximum s

Interventions

  • OTHER Questionnaire Administration
  • RADIATION Palliative Radiation Therapy
  • RADIATION Radiation Therapy Treatment Planning and Simulation

Study Locations (1)

California

  • UCLA / Jonsson Comprehensive Cancer Center - Los Angeles

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2014-11-12
Est. Completion 2018-06-20
Phase NA
Jonsson Comprehensive Cancer Center

321 total trials

What the finished NCT02575027 record still lists

NCT02575027 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 109-participant average among 199 other Glioblastoma trials with a reported enrollment target (91% lower).

The record links to 2 conditions, with Glioblastoma appearing as the primary indexed condition, and to 3 interventions - of which Questionnaire Administration is the first listed.

NCT02575027 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT02575027 about?

NCT02575027 is a clinical study titled "Palliative 4pi Radiotherapy in Treating Patients With Recurrent Glioblastoma Multiforme". This pilot clinical trial studies the feasibility of palliative 4pi radiotherapy in treating patients with glioblastoma multiforme that has come back after standard chemoradiation. A new radiotherapy delivery planning system, called 4pi radiotherapy, may help improve radiation delivery by improving ...

What is the current status of trial NCT02575027?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2014-11-12. Estimated completion is 2018-06-20.

What conditions does trial NCT02575027 study?

This clinical trial studies the following conditions: Glioblastoma, Recurrent Brain Neoplasm.

What interventions are being tested in trial NCT02575027?

The interventions under investigation include: Questionnaire Administration (OTHER), Palliative Radiation Therapy (RADIATION), Radiation Therapy Treatment Planning and Simulation (RADIATION).

Who is sponsoring clinical trial NCT02575027?

This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02575027 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Glioblastoma

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02575027's enrollment target sits among peer trials

10 189th of 199 higher than 6 of 199 other Glioblastoma trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Glioblastoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02575027, the US trial registry maintained by the National Library of Medicine. NCT02575027 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.