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NCT02439255 · ClinicalTrials.gov registry record · NA
Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers
A NA study of Tobacco Use Disorder and Healthy Subject, sponsored by Ohio State University Comprehensive Cancer Center.
- Completed
- Registry status
- NA
- Development phase
- 148
- Enrollment target
- 1
- Study location
NCT02439255: Completed NA study of Tobacco Use Disorder and Healthy Subject, sponsored by Ohio State University Comprehensive Cancer Center.
NCT02439255 is a NA study of Tobacco Use Disorder and Healthy Subject that has completed, run by Ohio State University Comprehensive Cancer Center. The registered enrollment target is 148 participants, below the 237-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (38% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02439255, a NA study of Tobacco Use Disorder and Healthy Subject, has completed, sponsored by Ohio State University Comprehensive Cancer Center.
- COMPLETED
- Registry status
- NA
- Development phase
- 148 participants
- Enrollment target
- 1
- Study location
Study Summary
This randomized clinical trial studies the effects of black raspberry compounds (phytochemicals) on the bacteria in the mouth (oral microbiome) of current smokers and non-smokers. The oral microbiome protects the body from pathogenic bacteria. Smoking alters the oral microbiome and may increase the susceptibility to cancer by modulating normal host-bacteria interactions. Black raspberry phytochemicals may protect the oral microbiome of smokers and may lower their risk of developing oral cancer.
Primary Outcome
The analyses of the microbial shift data will use a two-factor (smoking and berry treatment) ANOVA model with interaction on the post-treatment minus baseline differences between appropriately transformed data. Phylogenetic distances and community similarity and diversity will be computed from the sequence data. The sensitivity of the phylogenetic analysis to the uncertain knowledge of the phylogenetic relationships will be examined using draws from the posterior distribution of trees in a Mr. B
Conditions Studied
Interventions
- OTHER Placebo
- OTHER Laboratory Biomarker Analysis
- OTHER Screening Questionnaire Administration
- DIETARY_SUPPLEMENT Phytochemical
Study Locations (1)
Ohio
- Arthur G. James Cancer Hospital and Solove Research Institute at Ohio State University Medical Center - Columbus
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 148 participants |
| Start Date | 2015-12-04 |
| Est. Completion | 2022-04-30 |
| Phase | NA |
What the finished NCT02439255 record still lists
NCT02439255 is an interventional study that assigns participants to a tested intervention. The registered 148 participants enrollment target is mid-sized for trials with a published cap, below the 237-participant average among 70 other Tobacco Use Disorder trials with a reported enrollment target (38% lower).
The record links to 2 conditions, with Tobacco Use Disorder appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT02439255 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT02439255 about?
NCT02439255 is a clinical study titled "Effect of Black Raspberry Phytochemicals on Oral Microbiome in Current Smokers and Non-smokers". This randomized clinical trial studies the effects of black raspberry compounds (phytochemicals) on the bacteria in the mouth (oral microbiome) of current smokers and non-smokers. The oral microbiome protects the body from pathogenic bacteria. Smoking alters the oral microbiome and may increase the ...
What is the current status of trial NCT02439255?
This trial is currently completed. It is a NA study. The enrollment target is 148 participants. The study started on 2015-12-04. Estimated completion is 2022-04-30.
What conditions does trial NCT02439255 study?
This clinical trial studies the following conditions: Tobacco Use Disorder, Healthy Subject.
What interventions are being tested in trial NCT02439255?
The interventions under investigation include: Placebo (OTHER), Laboratory Biomarker Analysis (OTHER), Screening Questionnaire Administration (OTHER), Phytochemical (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT02439255?
This trial is sponsored by Ohio State University Comprehensive Cancer Center, which has 341 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02439255 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco Use Disorder
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02439255's enrollment target sits among peer trials
148 30th of 70 higher than 41 of 70 other Tobacco Use Disorder trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco Use Disorder trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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