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NCT02343120 · ClinicalTrials.gov registry record · Phase 1
Study of the Safety and Pharmacokinetics of BGB-3111 in Subjects With B-Cell Lymphoid Malignancies
A Phase 1 study of B-cell Malignancies, sponsored by BeiGene.
- Completed
- Registry status
- Phase 1
- Development phase
- 385
- Enrollment target
- 20
- Study locations
NCT02343120: Completed Phase 1 study of B-cell Malignancies, sponsored by BeiGene.
NCT02343120 is a Phase 1 study of B-cell Malignancies that has completed, run by BeiGene. The registered enrollment target is 385 participants, above the 270-participant average among 6 other B-cell Malignancies trials with a reported enrollment target (43% higher). The trial reports 20 study locations across 10 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02343120, a Phase 1 study of B-cell Malignancies, has completed, sponsored by BeiGene.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 385 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study evaluated the safety, tolerability, pharmacokinetic profile and efficacy of BGB-3111 in participants with B-cell lymphoid malignancies.
Primary Outcome
Number of participants with adverse events and serious adverse events, including clinically relevant physical examinations and laboratory measurements
Conditions Studied
Interventions
- DRUG Zanubrutinib
Study Locations (20)
Victoria
- Monash Health - Clayton
- Austin Health - Heidelberg
- St Vincent's Hospital - Melbourne
- Peter MacCallum Cancer Centre, East Melbourne - Parkville
- Melbourne Health - Parkville
Other
- Policlinico S.Orsola Malpighi, AOU di Bologna - Bologna
- Ospedale Maggiore Policlinico, Fondazione IRCCS Ca' Granda - Milan
- North Shore Hospital - Auckland
- Dong-A University Medical Centre - Busan
- Inje University Busan Paik Hospital - Busan
New South Wales
- Concord Repatriation General Hospital - Concord
- St George Hospital - Sydney
- Westmead Hospital - Westmead
Arizona
- Banner MD Anderson Cancer Centre - Gilbert
Michigan
- University of Michigan - Ann Arbor
Minnesota
- Mayo Clinic - Rochester
Texas
- M.D. Anderson Cancer Center - Houston
Queensland
- Princess Alexandra Hospital - Brisbane
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 385 participants |
| Start Date | 2014-09-04 |
| Est. Completion | 2021-03-31 |
| Phase | Phase 1 |
What the finished NCT02343120 record still lists
NCT02343120 is an interventional study that assigns participants to a tested intervention. The registered 385 participants enrollment target is mid-sized for trials with a published cap, above the 270-participant average among 6 other B-cell Malignancies trials with a reported enrollment target (43% higher).
The record links to 1 condition, with B-cell Malignancies appearing as the primary indexed condition, and to 1 intervention - of which Zanubrutinib is the first listed.
NCT02343120 names 20 study sites across 10 states, led by Victoria, Other, New South Wales.
Frequently Asked Questions
What is clinical trial NCT02343120 about?
NCT02343120 is a clinical study titled "Study of the Safety and Pharmacokinetics of BGB-3111 in Subjects With B-Cell Lymphoid Malignancies". This study evaluated the safety, tolerability, pharmacokinetic profile and efficacy of BGB-3111 in participants with B-cell lymphoid malignancies.
What is the current status of trial NCT02343120?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 385 participants. The study started on 2014-09-04. Estimated completion is 2021-03-31.
What conditions does trial NCT02343120 study?
This clinical trial studies the following conditions: B-cell Malignancies.
What interventions are being tested in trial NCT02343120?
The interventions under investigation include: Zanubrutinib (DRUG).
Who is sponsoring clinical trial NCT02343120?
This trial is sponsored by BeiGene, which has 65 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02343120 being conducted?
This trial has 20 study locations across Arizona, Michigan, Minnesota, Texas, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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