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NCT02301364 · ClinicalTrials.gov registry record · Phase 2
Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)
A Phase 2 study of Lymphoma and Primary Central Nervous System Lymphoma, sponsored by Memorial Sloan Kettering Cancer Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 4
- Enrollment target
- 4
- Study locations
NCT02301364: Completed Phase 2 study of Lymphoma and Primary Central Nervous System Lymphoma, sponsored by Memorial Sloan Kettering Cancer Center.
NCT02301364 is a Phase 2 study of Lymphoma and Primary Central Nervous System Lymphoma that has completed, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 4 participants, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (99% lower). The trial reports 4 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02301364, a Phase 2 study of Lymphoma and Primary Central Nervous System Lymphoma, has completed, sponsored by Memorial Sloan Kettering Cancer Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 4 participants
- Enrollment target
- 4
- Study locations
Study Summary
The purpose of this study is to find out what effects, good and/or bad, Buparlisib (also known as BKM120) has on lymphoma and the central nervous system.
Primary Outcome
Progression-free survival (PFS) is defined as the time from the date of treatment start to the date of the first documented PD or death due to any cause. PFS will be based on the investigator's assessment of MRI, CSF studies and clinical presentation.
Conditions Studied
Interventions
- DRUG Buparlisib (BKM120)
Study Locations (4)
New York
- Memorial Sloan Kettering Cancer Center @ Suffolk - Commack
- Memorial Sloan Kettering West Harrison - Harrison
- Memorial Sloan Kettering Cancer Center - New York
New Jersey
- Memoral Sloan Kettering Cancer Center - Basking Ridge
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 4 participants |
| Start Date | 2014-11-20 |
| Est. Completion | 2016-10-11 |
| Phase | Phase 2 |
What the finished NCT02301364 record still lists
NCT02301364 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 4 participants, a relatively small participant target, below the 484-participant average among 299 other Lymphoma trials with a reported enrollment target (99% lower).
The record links to 3 conditions, with Lymphoma appearing as the primary indexed condition, and to 1 intervention - of which Buparlisib (BKM120) is the first listed.
NCT02301364 reports a single indexed study location in New York, New Jersey.
Frequently Asked Questions
What is clinical trial NCT02301364 about?
NCT02301364 is a clinical study titled "Buparlisib (BKM120) In Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL) and Recurrent/Refractory Secondary Central Nervous System Lymphoma (SCNSL)". The purpose of this study is to find out what effects, good and/or bad, Buparlisib (also known as BKM120) has on lymphoma and the central nervous system.
What is the current status of trial NCT02301364?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 4 participants. The study started on 2014-11-20. Estimated completion is 2016-10-11.
What conditions does trial NCT02301364 study?
This clinical trial studies the following conditions: Lymphoma, Primary Central Nervous System Lymphoma, Recurrent/Refractory Secondary Central Nervous System Lymphoma.
What interventions are being tested in trial NCT02301364?
The interventions under investigation include: Buparlisib (BKM120) (DRUG).
Who is sponsoring clinical trial NCT02301364?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02301364 being conducted?
This trial has 4 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Lymphoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02301364's enrollment target sits among peer trials
4 292nd of 299 higher than 8 of 299 other Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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