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NCT02278354 · ClinicalTrials.gov registry record · Phase 1
Tau Imaging in Professional Fighters
A Phase 1 study of Alzheimers Disease, sponsored by Avid Radiopharmaceuticals.
- Completed
- Registry status
- Phase 1
- Development phase
- 35
- Enrollment target
- 1
- Study location
NCT02278354: Completed Phase 1 study of Alzheimers Disease, sponsored by Avid Radiopharmaceuticals.
NCT02278354 is a Phase 1 study of Alzheimers Disease that has completed, run by Avid Radiopharmaceuticals. The registered enrollment target is 35 participants, below the 3,926-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02278354, a Phase 1 study of Alzheimers Disease, has completed, sponsored by Avid Radiopharmaceuticals.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 35 participants
- Enrollment target
- 1
- Study location
Study Summary
Subjects enrolled in the Professional Fighters Brain Health Study (PFBHS) will receive flortaucipir to explore its use as a biomarker for brain injury related to repetitive head trauma and to examine the relationship between clinical presentation and tau deposition.
Primary Outcome
Standard Uptake Value Ratio (SUVr) by subject enrollment group (cognitive impaired/normal) across weighted cortical average, frontal, temporal, parietal, and occipital brain regions. For SUVr, a value of 1 or lower signifies no flortaucipir activity above background, values greater than 1 signify increasing flortaucipir activity in the brain.
Conditions Studied
Interventions
- DRUG Flortaucipir F18
- PROCEDURE Brain PET scan
Study Locations (1)
Nevada
- Cleveland Clinic Lou Ruvo Center for Brain Health - Las Vegas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 35 participants |
| Start Date | 2015-02-18 |
| Est. Completion | 2017-02-03 |
| Phase | Phase 1 |
What the finished NCT02278354 record still lists
NCT02278354 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 35 participants, a relatively small participant target, below the 3,926-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Alzheimers Disease appearing as the primary indexed condition, and to 2 interventions - of which Flortaucipir F18 is the first listed.
NCT02278354 reports a single indexed study location in Nevada.
Frequently Asked Questions
What is clinical trial NCT02278354 about?
NCT02278354 is a clinical study titled "Tau Imaging in Professional Fighters". Subjects enrolled in the Professional Fighters Brain Health Study (PFBHS) will receive flortaucipir to explore its use as a biomarker for brain injury related to repetitive head trauma and to examine the relationship between clinical presentation and tau deposition.
What is the current status of trial NCT02278354?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2015-02-18. Estimated completion is 2017-02-03.
What conditions does trial NCT02278354 study?
This clinical trial studies the following conditions: Alzheimers Disease.
What interventions are being tested in trial NCT02278354?
The interventions under investigation include: Flortaucipir F18 (DRUG), Brain PET scan (PROCEDURE).
Who is sponsoring clinical trial NCT02278354?
This trial is sponsored by Avid Radiopharmaceuticals, which has 42 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02278354 being conducted?
This trial has 1 study location across Nevada. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Alzheimers Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02278354's enrollment target sits among peer trials
35 114th of 147 higher than 33 of 147 other Alzheimers Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimers Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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