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NCT02213484 · ClinicalTrials.gov registry record
Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes
A clinical trial of Turner Syndrome and Marfan Syndrome, sponsored by University of Colorado, Denver.
- Completed
- Registry status
- 20
- Enrollment target
- 2
- Study locations
NCT02213484 is a study of Turner Syndrome and Marfan Syndrome that has completed, run by University of Colorado, Denver. The registered enrollment target is 20 participants, below the 518-participant average among 14 other Turner Syndrome trials with a reported enrollment target (96% lower). The trial reports 2 study locations across 1 state.
The verdict
NCT02213484, a study of Turner Syndrome and Marfan Syndrome, has completed, sponsored by University of Colorado, Denver.
- COMPLETED
- Registry status
- 20 participants
- Enrollment target
- 2
- Study locations
Study Summary
The primary objective of this study is to determine whether specific patterns of circulating micro-ribonucleic acids (miRNAs) are associated with aortic aneurysm and dissection in patients with hereditary aortopathy syndromes. The most common of these syndromes is Marfan Syndrome (MFS), but several other recognized aortopathy syndromes are well characterized. The investigators propose the use of a simple blood test, from which miRNA profiles can be measured in individuals with aortopathy syndromes to be compared with miRNAs observed in a control population that has no known predisposition for aortic disease. The investigators hypothesize that microRNA profiles in individuals with Marfan syndrome, and related disorders, will be distinct from those seen in a control group. The investigators predict that up- or down-regulation of certain miRNAs will correlate with the presence and severity of aortic aneurysm, responses to medical therapy, and ultimately could be used to determine when an individual may be at risk of dissection.
Conditions Studied
Study Locations (2)
Colorado
- Children's Hospital Colorado - Aurora
- University of Colorado Hospital - Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2014-07-01 |
| Est. Completion | 2016-07-01 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02213484
The ClinicalTrials.gov registry entry for NCT02213484 describes a study currently listed as completed, categorized as an unspecified phase. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 518-participant average among 14 other Turner Syndrome trials with a reported enrollment target (96% lower). The listed sponsor is University of Colorado, Denver, which has 1,283 total studies on file at ClinicalTrials.gov.
The record links to 5 conditions, with Turner Syndrome appearing as the primary indexed condition, and to 0 interventions.
NCT02213484 reports 2 study locations spanning 1 distinct geographic area - top geographies include Colorado.
Frequently Asked Questions
What is clinical trial NCT02213484 about?
NCT02213484 is a clinical study titled "Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes". The primary objective of this study is to determine whether specific patterns of circulating micro-ribonucleic acids (miRNAs) are associated with aortic aneurysm and dissection in patients with hereditary aortopathy syndromes. The most common of these syndromes is Marfan Syndrome (MFS), but several ...
What is the current status of trial NCT02213484?
This trial is currently completed. The enrollment target is 20 participants. The study started on 2014-07-01. Estimated completion is 2016-07-01.
What conditions does trial NCT02213484 study?
This clinical trial studies the following conditions: Turner Syndrome, Marfan Syndrome, Loeys-Dietz Syndrome, Thoracic Aortic Aneurysm and Dissection Syndromes, Ehlers-Danlos Type IV Syndrome.
Who is sponsoring clinical trial NCT02213484?
This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02213484 being conducted?
This trial has 2 study locations across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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