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NCT06834594 · ClinicalTrials.gov registry record · Phase 4
Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome
A Phase 4 study of Turner Syndrome and Primary Ovarian Insufficiency (Poi), sponsored by Children's Mercy Hospital Kansas City.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT06834594: Recruiting Phase 4 study of Turner Syndrome and Primary Ovarian Insufficiency (Poi), sponsored by Children's Mercy Hospital Kansas City.
NCT06834594 is a Phase 4 study of Turner Syndrome and Primary Ovarian Insufficiency (Poi) that is actively recruiting participants, run by Children's Mercy Hospital Kansas City. The registered enrollment target is 40 participants, below the 516-participant average among 14 other Turner Syndrome trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06834594, a Phase 4 study of Turner Syndrome and Primary Ovarian Insufficiency (Poi), is actively recruiting participants, sponsored by Children's Mercy Hospital Kansas City.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Syndrome (TS) patients with primary ovarian insufficiency (POI) prescribed hormone replacement therapy (HRT).
Primary Outcome
PBAC is one of the most common scoring systems used in the literature to quantify menstrual blood loss (MBL) using a pictorial scoring system, with a higher score representing a larger MBL and a score \>100 qualifying as heavy menstrual bleeding
Conditions Studied
Interventions
- DRUG Micronized progesterone 200 MG
- DRUG Micronized Progesterone 100 MG
Study Locations (1)
Missouri
- Children's Mercy Hospital - Kansas City
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-07-31 |
| Est. Completion | 2026-07-31 |
| Phase | Phase 4 |
What NCT06834594 shows while recruiting
NCT06834594 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 516-participant average among 14 other Turner Syndrome trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Turner Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Micronized progesterone 200 MG is the first listed.
NCT06834594 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT06834594 about?
NCT06834594 is a clinical study titled "Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome". This is a single-site open label non-randomized study comparing effects of sequential versus continuous use of progesterone supplementation amongst Turner Syndrome (TS) patients with primary ovarian insufficiency (POI) prescribed hormone replacement therapy (HRT).
What is the current status of trial NCT06834594?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 40 participants. The study started on 2025-07-31. Estimated completion is 2026-07-31.
What conditions does trial NCT06834594 study?
This clinical trial studies the following conditions: Turner Syndrome, Primary Ovarian Insufficiency (Poi).
What interventions are being tested in trial NCT06834594?
The interventions under investigation include: Micronized progesterone 200 MG (DRUG), Micronized Progesterone 100 MG (DRUG).
Who is sponsoring clinical trial NCT06834594?
This trial is sponsored by Children's Mercy Hospital Kansas City, which has 184 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06834594 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Turner Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06834594's enrollment target sits among peer trials
40 13th of 14 higher than 2 of 14 other Turner Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Turner Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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