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ClinicalTrials.gov 8 recruiting now full pipeline small index

Turner Syndrome: full-pipeline trial registry

8 of 15 indexed Turner Syndrome trials are currently recruiting.

Corpus placement: #1,140 of 28,707 conditions by registered trial count.

15 US clinical trials · 8 currently recruiting · #1,140 of 28,707 conditions by registered trial count

Turner Syndrome: 15 US clinical trials tracked, 8 recruiting.

Turner Syndrome is the subject of 15 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 2 of these trials.

Enrollment posture brief

Registry condition turner-syndrome

OPEN 8 | RECR 53% | LATE 4 | EARLY 3 | RANK #1140 | SPON 2

Nearest open-share peer: Beta-Thalassemia (53% recruiting · 15 trials)

Advanced Lung Non-Small Cell53.3%Turner Syndrome (this)53%AIDS26.7%Adult Acute Myeloid Leukemia0%Adult Glioblastoma0%
Open-enrollment share among volume-matched conditions near Turner Syndrome

Turner Syndrome lists 8 open slots (53% of 15 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Turner Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Turner Syndrome is recruiting above its size-band peers.

    8 of 15 indexed trials (53.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Turner Syndrome trials is spread across many organizations.

    University of Colorado, Denver accounts for 2 of 15 trials (13.3%). 14 distinct sponsors appear on at least one study for this condition label.

  3. Typical Turner Syndrome enrolment sits around 100 participants.

    Median target enrolment is 100 among the 15 trials that report a genuine target (sentinel values excluded). 7 of those (46.7%) plan for fewer than 100 participants.

  4. Turner Syndrome splits between interventional and observational designs.

    7 interventional and 8 observational studies make up this index (46.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 23Phase 33Phase 41

Open and recent trials

15 total, page 1 of 1

RECRUITING 5,000 participants

Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry

University of Colorado, Denver

NCT05052606

RECRUITING 400 participants

Natural History of Noncirrhotic Portal Hypertension

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT02417740

RECRUITING 200 participants

UTHealth Turner Syndrome Research Registry

The University of Texas Health Science Center, Houston

NCT03185702

RECRUITING 200 participants

Gonadal Tissue Freezing for Fertility Preservation in Individuals at Risk for Ovarian Dysfunction, Premature Ovarian Insufficiency and Clinically Indicated Gonadectomy

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT04948658

RECRUITING Phase 3 186 participants

Trial Investigating the Efficacy and Safety of Weekly Lonapegsomatropin Compared to Daily Somatropin in Children and Adolescents With Short Stature or Growth Failure Due to Growth Hormone Sufficient Disorders

Ascendis Pharma A/S

NCT07221851

RECRUITING Phase 2 54 participants

A Basket Study of Vosoritide in Children With Turner Syndrome, Short Stature Homeobox-Containing Gene Deficiency, and Noonan Syndrome With Inadequate Growth During or After Human Growth Hormone Treatment

BioMarin Pharmaceutical

NCT06668805

RECRUITING Phase 4 40 participants

Bleeding Patterns in Sequential and Continuous Progesterone Supplementation in Adolescents With Turner Syndrome

Children's Mercy Hospital Kansas City

NCT06834594

RECRUITING Phase 2 20 participants

Vosoritide for Short Stature in Turner Syndrome

Roopa Kanakatti Shankar, MBBS, MS

NCT05849389

ACTIVE NOT RECRUITING Phase 2 48 participants

A Trial to Investigate Different Doses of Lonapegsomatropin Compared to Somatropin in Individuals With Turner Syndrome

Ascendis Pharma Endocrinology Division A/S

NCT05690386

ACTIVE NOT RECRUITING Phase 3 47 participants

A Research Study Looking at How Safe Somapacitan is and How Well it Works in Children Who Need Help to Grow - REAL 9

Novo Nordisk A/S

NCT05723835

COMPLETED 760 participants

Expanded Noninvasive Genomic Medical Assessment: The Enigma Study

Progenity

NCT02787486

COMPLETED 120 participants

Risk of Diabetes in Young Turner Syndrome Patients

Children's Hospital Medical Center, Cincinnati

NCT02160717

COMPLETED Phase 3 100 participants

The Effect of Growth Hormone in Very Young Girls With Turner Syndrome

Eli Lilly and Company

NCT00406926

COMPLETED 72 participants

Dry Eye in Women With Turner Syndrome and Women With Premature Ovarian Failure

National Eye Institute (NEI)

NCT00471731

COMPLETED 20 participants

Micro RNAs as a Marker of Aortic Aneurysm in Hereditary Aortopathy Syndromes

University of Colorado, Denver

NCT02213484

Phase Distribution

PhaseTrial count
Phase 2 3
Phase 3 3
Phase 4 1

Named interventions

Most-linked intervention names on Turner Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Somatropin Drug
2 trials
Blood sampling for Laboratory Developed Test (LDT) analysis Other
1 trials
Lonapegsomatropin Biological
1 trials
Somapacitan Drug
1 trials
Somatropin Pen Injector Combination
1 trials
Lonapegsomatropin [SKYTROFA®] Combination
1 trials
Micronized Progesterone 100 MG Drug
1 trials
Micronized progesterone 200 MG Drug
1 trials

US sites by state

Facility locations filed on Turner Syndrome trials. A trial with sites in several states counts in each.

Colorado 7 trials
Texas 6 trials
Ohio 4 trials
North Carolina 4 trials
Minnesota 4 trials
Idaho 4 trials
California 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Turner Syndrome page

15 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Turner Syndrome condition card totals 15 registered trials; most-linked intervention Somatropin; top US site state Colorado. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.