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NCT02213289 · ClinicalTrials.gov registry record · Phase 2

PANGEA-IMBBP: Personalized Antibodies for Gastro-Esophageal Adenocarcinoma - A 1st Pilot Metastatic Trial of Biologics Beyond Progression

A Phase 2 study, sponsored by University of Chicago.

Completed
Registry status
Phase 2
Development phase
80
Enrollment target

NCT02213289: Completed Phase 2 study, sponsored by University of Chicago.

NCT02213289 is a Phase 2 study that has completed, run by University of Chicago. The registered enrollment target is 80 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02213289, a Phase 2 study, has completed, sponsored by University of Chicago.

COMPLETED
Registry status
Phase 2
Development phase
80 participants
Enrollment target

Study Summary

The purpose of this study is to determine if doctors can use the results of special tests of subjects tumor tissue, that will look for specific abnormalities in the tumor, to choose a specific drug that is targeted to work against that abnormality (called molecular profiling) and to see what effects (good and/or bad) that targeted drug has on subjects cancer when it is given with standard chemotherapy.

Primary Outcome

Time from enrollment to death from any cause.

Interventions

  • DRUG Trastuzumab
  • DRUG Nivolumab
  • DRUG Ramucirumab
  • DRUG Bemarituzumab
  • DRUG ABT-806

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2015-01-20
Est. Completion 2020-08-20
Phase Phase 2
University of Chicago

796 total trials

What the finished NCT02213289 record still lists

NCT02213289 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (40% lower).

The record links to 0 conditions, and to 5 interventions - of which Trastuzumab is the first listed.

NCT02213289 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02213289 about?

NCT02213289 is a clinical study titled "PANGEA-IMBBP: Personalized Antibodies for Gastro-Esophageal Adenocarcinoma - A 1st Pilot Metastatic Trial of Biologics Beyond Progression". The purpose of this study is to determine if doctors can use the results of special tests of subjects tumor tissue, that will look for specific abnormalities in the tumor, to choose a specific drug that is targeted to work against that abnormality (called molecular profiling) and to see what effects...

What is the current status of trial NCT02213289?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 80 participants. The study started on 2015-01-20. Estimated completion is 2020-08-20.

What interventions are being tested in trial NCT02213289?

The interventions under investigation include: Trastuzumab (DRUG), Nivolumab (DRUG), Ramucirumab (DRUG), Bemarituzumab (DRUG), ABT-806 (DRUG).

Who is sponsoring clinical trial NCT02213289?

This trial is sponsored by University of Chicago, which has 796 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02213289's enrollment target sits among peer trials

80 842nd of 2000 higher than 1,117 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02213289, the US trial registry maintained by the National Library of Medicine. NCT02213289 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.