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NCT02134925 · ClinicalTrials.gov registry record · Phase 2
Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps
A Phase 2 study of Colorectal Carcinoma and Colorectal Adenoma, sponsored by National Cancer Institute (NCI).
- Active
- Registry status
- Phase 2
- Development phase
- 110
- Enrollment target
- 7
- Study locations
NCT02134925 is a Phase 2 study of Colorectal Carcinoma and Colorectal Adenoma that is active but no longer recruiting, run by National Cancer Institute (NCI). The registered enrollment target is 110 participants, below the 1,094-participant average among 53 other Colorectal Carcinoma trials with a reported enrollment target (90% lower). The trial reports 7 study locations across 5 states.
The verdict
NCT02134925, a Phase 2 study of Colorectal Carcinoma and Colorectal Adenoma, is active but no longer recruiting, sponsored by National Cancer Institute (NCI).
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 110 participants
- Enrollment target
- 7
- Study locations
Study Summary
This randomized phase II clinical trial studies how well MUC1 peptide-poly-ICLC adjuvant vaccine works in treating patients with newly diagnosed advanced colon polyps (adenomatous polyps). Adenomatous polyps are growths in the colon that may develop into colorectal cancer over time. Vaccines made from peptides may help the body build an effective immune response to kill polyp cells. MUC1 peptide-poly-ICLC adjuvant vaccine may also prevent the recurrence of adenomatous polyps and may prevent the development of colorectal cancer.
Conditions Studied
Interventions
- OTHER Quality-of-Life Assessment
- OTHER Saline
- OTHER Laboratory Biomarker Analysis
- BIOLOGICAL MUC1 Peptide-Poly-ICLC Vaccine
Study Locations (7)
Pennsylvania
- Thomas Jefferson University Hospital - Philadelphia
- Fox Chase Cancer Center - Philadelphia
- University of Pittsburgh Cancer Institute (UPCI) - Pittsburgh
Massachusetts
- Massachusetts General Hospital Cancer Center - Boston
Minnesota
- Mayo Clinic in Rochester - Rochester
Missouri
- Kansas City Veterans Affairs Medical Center - Kansas City
Other
- University of Puerto Rico - San Juan
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2014-06-23 |
| Est. Completion | 2026-03-06 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02134925
The ClinicalTrials.gov registry entry for NCT02134925 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 110 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,094-participant average among 53 other Colorectal Carcinoma trials with a reported enrollment target (90% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 4 conditions, with Colorectal Carcinoma appearing as the primary indexed condition, and to 4 interventions - of which Quality-of-Life Assessment is the first listed.
NCT02134925 reports 7 study locations spanning 5 distinct geographic areas - top geographies include Pennsylvania, Massachusetts, Minnesota.
Frequently Asked Questions
What is clinical trial NCT02134925 about?
NCT02134925 is a clinical study titled "Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps". This randomized phase II clinical trial studies how well MUC1 peptide-poly-ICLC adjuvant vaccine works in treating patients with newly diagnosed advanced colon polyps (adenomatous polyps). Adenomatous polyps are growths in the colon that may develop into colorectal cancer over time. Vaccines made fr...
What is the current status of trial NCT02134925?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 110 participants. The study started on 2014-06-23. Estimated completion is 2026-03-06.
What conditions does trial NCT02134925 study?
This clinical trial studies the following conditions: Colorectal Carcinoma, Colorectal Adenoma, Colorectal Adenoma With Severe Dysplasia, Colorectal Tubulovillous Adenoma.
What interventions are being tested in trial NCT02134925?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Saline (OTHER), Laboratory Biomarker Analysis (OTHER), MUC1 Peptide-Poly-ICLC Vaccine (BIOLOGICAL).
Who is sponsoring clinical trial NCT02134925?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02134925 being conducted?
This trial has 7 study locations across Massachusetts, Minnesota, Missouri, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.