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NCT02124941 · ClinicalTrials.gov registry record · Phase 1
Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS
A Phase 1 study of Healthy and Cocaine Dependence, sponsored by Yale University.
- Completed
- Registry status
- Phase 1
- Development phase
- 6
- Enrollment target
- 1
- Study location
NCT02124941: Completed Phase 1 study of Healthy and Cocaine Dependence, sponsored by Yale University.
NCT02124941 is a Phase 1 study of Healthy and Cocaine Dependence that has completed, run by Yale University. The registered enrollment target is 6 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02124941, a Phase 1 study of Healthy and Cocaine Dependence, has completed, sponsored by Yale University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 6 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to look at the relationship between brain glucose utilization, neurotransmission (e.g., glutamate, also known as the main excitatory amino-acid neurotransmitter in the brain), and synaptic density. This relationship will be explored in the brain's prefrontal cortex, an area important in decision-making and impulsivity.
Conditions Studied
Interventions
- DRUG N-acetyl cysteine
- DIAGNOSTIC_TEST [18F]FDG PET scan
- DIAGNOSTIC_TEST 1H MRS
- DIAGNOSTIC_TEST [11C]APP311 PET scan
Study Locations (1)
Connecticut
- Connecticut Mental Health Center - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2014-02 |
| Est. Completion | 2022-08-14 |
| Phase | Phase 1 |
What the finished NCT02124941 record still lists
NCT02124941 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Healthy appearing as the primary indexed condition, and to 4 interventions - of which N-acetyl cysteine is the first listed.
NCT02124941 reports a single indexed study location in Connecticut.
Frequently Asked Questions
What is clinical trial NCT02124941 about?
NCT02124941 is a clinical study titled "Glutamate-Glutamine Cycling (VCYC) During Cocaine Abstinence Using 1H-MRS". This study is designed to look at the relationship between brain glucose utilization, neurotransmission (e.g., glutamate, also known as the main excitatory amino-acid neurotransmitter in the brain), and synaptic density. This relationship will be explored in the brain's prefrontal cortex, an area im...
What is the current status of trial NCT02124941?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 6 participants. The study started on 2014-02. Estimated completion is 2022-08-14.
What conditions does trial NCT02124941 study?
This clinical trial studies the following conditions: Healthy, Cocaine Dependence.
What interventions are being tested in trial NCT02124941?
The interventions under investigation include: N-acetyl cysteine (DRUG), [18F]FDG PET scan (DIAGNOSTIC_TEST), 1H MRS (DIAGNOSTIC_TEST), [11C]APP311 PET scan (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT02124941?
This trial is sponsored by Yale University, which has 1,492 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02124941 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02124941's enrollment target sits among peer trials
6 1075th of 1090 higher than 7 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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