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NCT02104310 · ClinicalTrials.gov registry record
A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in Gliomas
A clinical trial of Malignant Glioma, sponsored by Mayo Clinic.
- Active
- Registry status
- 25
- Enrollment target
- 1
- Study location
NCT02104310: Active study of Malignant Glioma, sponsored by Mayo Clinic.
NCT02104310 is a study of Malignant Glioma that is active but no longer recruiting, run by Mayo Clinic. The registered enrollment target is 25 participants, below the 91-participant average among 40 other Malignant Glioma trials with a reported enrollment target (73% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02104310, a study of Malignant Glioma, is active but no longer recruiting, sponsored by Mayo Clinic.
- ACTIVE NOT RECRUITING
- Registry status
- 25 participants
- Enrollment target
- 1
- Study location
Study Summary
For most brain tumors, radiation treatment is guided by a Magnetic Resonance Imaging (MRI) scan. In this study, information from a special scan, called a Positron Emission Tomography/ Computed Tomography (PET/CT) scan using an amino acid called Fluorine-18-L-dihydroxyphenylalanine (18F-DOPA) will also be used. This type of scan has shown promise in being able to better distinguish tumor from normal brain tissue and may help to more accurately plan radiation treatment. This type of scan can also assist the radiation oncologist in identifying the most aggressive regions of the tumor. The goal of this study is to compare the 18F-DOPA PET/CT scan with the MRI scan for identifying where the disease is that needs to be treated with radiation.
Primary Outcome
The primary endpoint for this pilot study will be to compare radiotherapy treatment volumes defined by conventional MR-only with treatment volumes defined with both 18F-DOPA PET and conventional MR information
Conditions Studied
Interventions
- DRUG Fluorine-18-L-dihydroxyphenylalanine
Study Locations (1)
Minnesota
- Mayo Clinic - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 25 participants |
| Start Date | 2014-04 |
| Est. Completion | 2031-03 |
What the registry record for NCT02104310 still lists
NCT02104310 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 25 participants, a relatively small participant target, below the 91-participant average among 40 other Malignant Glioma trials with a reported enrollment target (73% lower).
The record links to 1 condition, with Malignant Glioma appearing as the primary indexed condition, and to 1 intervention - of which Fluorine-18-L-dihydroxyphenylalanine is the first listed.
NCT02104310 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT02104310 about?
NCT02104310 is a clinical study titled "A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in Gliomas". For most brain tumors, radiation treatment is guided by a Magnetic Resonance Imaging (MRI) scan. In this study, information from a special scan, called a Positron Emission Tomography/ Computed Tomography (PET/CT) scan using an amino acid called Fluorine-18-L-dihydroxyphenylalanine (18F-DOPA) will al...
What is the current status of trial NCT02104310?
This trial is currently active not recruiting. The enrollment target is 25 participants. The study started on 2014-04. Estimated completion is 2031-03.
What conditions does trial NCT02104310 study?
This clinical trial studies the following conditions: Malignant Glioma.
What interventions are being tested in trial NCT02104310?
The interventions under investigation include: Fluorine-18-L-dihydroxyphenylalanine (DRUG).
Who is sponsoring clinical trial NCT02104310?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02104310 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02104310's enrollment target sits among peer trials
25 30th of 40 higher than 11 of 40 other Malignant Glioma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Malignant Glioma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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