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NCT02063217 · ClinicalTrials.gov registry record · NA

Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction

A NA study of Amyloid-beta, sponsored by Washington University School of Medicine.

Completed
Registry status
NA
Development phase
36
Enrollment target
1
Study location

NCT02063217: Completed NA study of Amyloid-beta, sponsored by Washington University School of Medicine.

NCT02063217 is a NA study of Amyloid-beta that has completed, run by Washington University School of Medicine. The registered enrollment target is 36 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02063217, a NA study of Amyloid-beta, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
NA
Development phase
36 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to change the concentration of amyloid-beta in human cerebrospinal fluid (CSF) through modulation of the sleep-wake cycle.

Primary Outcome

Overnight (01:00 to 11:00) differences in CSF amyloid beta from baseline (07:00 to 19:00) between 1) sleep-deprived and control participants and 2) sleep-induced and control participants.

Conditions Studied

Interventions

  • BEHAVIORAL Sleep deprivation
  • DRUG Sodium Oxybate

Study Locations (1)

Missouri

  • Washington University Medical School - St Louis

Trial Details

FieldValue
Enrollment Target 36 participants
Start Date 2013-12
Est. Completion 2016-07
Phase NA

What the finished NCT02063217 record still lists

NCT02063217 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Amyloid-beta appearing as the primary indexed condition, and to 2 interventions - of which Sleep deprivation is the first listed.

NCT02063217 reports a single indexed study location in Missouri.

Frequently Asked Questions

What is clinical trial NCT02063217 about?

NCT02063217 is a clinical study titled "Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction". The purpose of this study is to change the concentration of amyloid-beta in human cerebrospinal fluid (CSF) through modulation of the sleep-wake cycle.

What is the current status of trial NCT02063217?

This trial is currently completed. It is a NA study. The enrollment target is 36 participants. The study started on 2013-12. Estimated completion is 2016-07.

What conditions does trial NCT02063217 study?

This clinical trial studies the following conditions: Amyloid-beta.

What interventions are being tested in trial NCT02063217?

The interventions under investigation include: Sleep deprivation (BEHAVIORAL), Sodium Oxybate (DRUG).

Who is sponsoring clinical trial NCT02063217?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02063217 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT02063217's enrollment target sits among peer trials

36 1541st of 2000 higher than 437 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02063217, the US trial registry maintained by the National Library of Medicine. NCT02063217 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.