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NCT02057510 · ClinicalTrials.gov registry record
Observational Study of Dental Outcomes in Head and Neck Cancer Patients
A clinical trial of Head and Neck Cancer and Xerostomia, sponsored by Wake Forest University Health Sciences.
- Active
- Registry status
- 575
- Enrollment target
- 6
- Study locations
NCT02057510: Active study of Head and Neck Cancer and Xerostomia, sponsored by Wake Forest University Health Sciences.
NCT02057510 is a study of Head and Neck Cancer and Xerostomia that is active but no longer recruiting, run by Wake Forest University Health Sciences. The registered enrollment target is 575 participants, above the 259-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (122% higher). The trial reports 6 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02057510, a study of Head and Neck Cancer and Xerostomia, is active but no longer recruiting, sponsored by Wake Forest University Health Sciences.
- ACTIVE NOT RECRUITING
- Registry status
- 575 participants
- Enrollment target
- 6
- Study locations
Study Summary
The purpose of this study is to measure the two-year rate of tooth loss in patients who have received external beam radiation therapy with curative intent for head and neck cancer. The study will also evaluate the sequelae of radiation therapy and oral complications that may occur as a result to receiving radiation therapy.
Primary Outcome
The primary outcome measure is the two-year rate of tooth loss in patients who have received at least one session of external beam radiation therapy with curative intent for head and neck cancer. "Tooth loss" will be defined as a dental extraction that has been performed or recommended. Since dental extractions are often avoided in this population because of the increased risk of osteoradionecrosis (ORN), tooth loss will also include teeth having a dental procedure to avoid extraction of a toot
Conditions Studied
Study Locations (6)
North Carolina
- University of North Carolina - School of Dentistry - Chapel Hill
- Carolinas Medical Center - Dental Clinic - Charlotte
Connecticut
- University of Connecticut Health Center - School of Dental Medicine - Farmington
Massachusetts
- Brigham and Women's Hospital - Boston
New York
- New York University - College of Dentistry - New York
Pennsylvania
- University of Pennsylvania - School of Dental Medicine - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 575 participants |
| Start Date | 2014-02 |
| Est. Completion | 2026-06-30 |
What the registry record for NCT02057510 still lists
NCT02057510 is an observational study that tracks outcomes without assigning an intervention. The registered 575 participants enrollment target is mid-sized for trials with a published cap, above the 259-participant average among 250 other Head and Neck Cancer trials with a reported enrollment target (122% higher).
The record links to 4 conditions, with Head and Neck Cancer appearing as the primary indexed condition, and to 0 interventions.
NCT02057510 lists 6 locations in 5 states (North Carolina, Connecticut, Massachusetts).
Frequently Asked Questions
What is clinical trial NCT02057510 about?
NCT02057510 is a clinical study titled "Observational Study of Dental Outcomes in Head and Neck Cancer Patients". The purpose of this study is to measure the two-year rate of tooth loss in patients who have received external beam radiation therapy with curative intent for head and neck cancer. The study will also evaluate the sequelae of radiation therapy and oral complications that may occur as a result to rec...
What is the current status of trial NCT02057510?
This trial is currently active not recruiting. The enrollment target is 575 participants. The study started on 2014-02. Estimated completion is 2026-06-30.
What conditions does trial NCT02057510 study?
This clinical trial studies the following conditions: Head and Neck Cancer, Xerostomia, Osteoradionecrosis, Dental Disease.
Who is sponsoring clinical trial NCT02057510?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02057510 being conducted?
This trial has 6 study locations across Connecticut, Massachusetts, New York, North Carolina, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Head and Neck Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT02057510's enrollment target sits among peer trials
575 20th of 250 higher than 231 of 250 other Head and Neck Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Head and Neck Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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