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NCT01978262 · ClinicalTrials.gov registry record · Phase 4

Immune and Hormone Response to Influenza Vaccine

A Phase 4 study of Healthy, sponsored by Johns Hopkins Bloomberg School of Public Health.

Completed
Registry status
Phase 4
Development phase
103
Enrollment target
1
Study location

NCT01978262: Completed Phase 4 study of Healthy, sponsored by Johns Hopkins Bloomberg School of Public Health.

NCT01978262 is a Phase 4 study of Healthy that has completed, run by Johns Hopkins Bloomberg School of Public Health. The registered enrollment target is 103 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (84% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01978262, a Phase 4 study of Healthy, has completed, sponsored by Johns Hopkins Bloomberg School of Public Health.

COMPLETED
Registry status
Phase 4
Development phase
103 participants
Enrollment target
1
Study location

Study Summary

The purpose of this pilot research project is to look at the effect of the inactivated influenza vaccine (seasonal flu shot) on early signs of immune or germ-fighting response known as cytokines or signal molecules. The investigators also want to see if the timing of vaccine administration has any effect on women's reproductive hormones. The investigators hypothesis is that influenza vaccine given right before ovulation may change the hormone levels usually seen after ovulation. Thi

Primary Outcome

To explore whether receipt of IIV during the second week of the menstrual cycle (i.e., the week prior to ovulation) is associated with changes in steroid hormone levels, particularly decreases in progesterone, following ovulation.

Conditions Studied

Interventions

  • BIOLOGICAL Seasonal Inactivated Influenza Vaccine

Study Locations (1)

Maryland

  • Center for Immunization Research; Johns Hopkins Bloomberg School of Public Health - Baltimore

Trial Details

FieldValue
Enrollment Target 103 participants
Start Date 2013-10
Est. Completion 2017-08
Phase Phase 4

What the finished NCT01978262 record still lists

NCT01978262 is an interventional study that assigns participants to a tested intervention. The registered 103 participants enrollment target is mid-sized for trials with a published cap, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (84% lower).

The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Seasonal Inactivated Influenza Vaccine is the first listed.

NCT01978262 reports a single indexed study location in Maryland.

Frequently Asked Questions

What is clinical trial NCT01978262 about?

NCT01978262 is a clinical study titled "Immune and Hormone Response to Influenza Vaccine". The purpose of this pilot research project is to look at the effect of the inactivated influenza vaccine (seasonal flu shot) on early signs of immune or germ-fighting response known as cytokines or signal molecules. The investigators also want to see if the timing of vaccine administration has any e...

What is the current status of trial NCT01978262?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 103 participants. The study started on 2013-10. Estimated completion is 2017-08.

What conditions does trial NCT01978262 study?

This clinical trial studies the following conditions: Healthy.

What interventions are being tested in trial NCT01978262?

The interventions under investigation include: Seasonal Inactivated Influenza Vaccine (BIOLOGICAL).

Who is sponsoring clinical trial NCT01978262?

This trial is sponsored by Johns Hopkins Bloomberg School of Public Health, which has 187 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01978262 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Healthy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01978262's enrollment target sits among peer trials

103 215th of 1090 higher than 875 of 1,090 other Healthy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01978262, the US trial registry maintained by the National Library of Medicine. NCT01978262 (mid enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.