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NCT01924481 · ClinicalTrials.gov registry record · NA
Effects of a Cocoa Shot on the Human Brain
A NA study of Caffeine and Flavonoids, sponsored by Wake Forest University Health Sciences.
- Completed
- Registry status
- NA
- Development phase
- 6
- Enrollment target
- 1
- Study location
NCT01924481: Completed NA study of Caffeine and Flavonoids, sponsored by Wake Forest University Health Sciences.
NCT01924481 is a NA study of Caffeine and Flavonoids that has completed, run by Wake Forest University Health Sciences. The registered enrollment target is 6 participants, below the 75-participant average among 6 other Caffeine trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01924481, a NA study of Caffeine and Flavonoids, has completed, sponsored by Wake Forest University Health Sciences.
- COMPLETED
- Registry status
- NA
- Development phase
- 6 participants
- Enrollment target
- 1
- Study location
Study Summary
The Hershey Company is interested in investigating the effects of various chocolate beverages on brain physiology and cognitive function. The main substances in the drinks that are known to influence the brain are caffeine (and related chemicals such as theobromine) and flavonoids. Flavonoids are chemical found in plants and are most commonly associated with antioxidant activity. Caffeine, chemicals related to caffeine, and flavonoids are all naturally occurring and all potentially alter brain physiology. This study will evaluate changes in brain blood flow and cognition following the consumption of drinks with various combinations of the Primary Ingredients. Caffeine is likely to have peak effects within 1-hour of ingesting the chocolate while the flavonoids are likely to have peak effects 3-4 hours after ingestion. The study proposed here will evaluate ingredients in a 4-arm cross-over double-blind design in an attempt to understand the differential effects of these compounds in chocolate drinks.
Primary Outcome
N-Back Task
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT High Caffeine
- DIETARY_SUPPLEMENT Low caffeine
- DIETARY_SUPPLEMENT High theobromine
- DIETARY_SUPPLEMENT low theobromine
- DIETARY_SUPPLEMENT No theobromine
Study Locations (1)
North Carolina
- Wake Forest University Health Sciences - Winston-Salem
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 6 participants |
| Start Date | 2013-09 |
| Est. Completion | 2013-10 |
| Phase | NA |
What the finished NCT01924481 record still lists
NCT01924481 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 6 participants, a relatively small participant target, below the 75-participant average among 6 other Caffeine trials with a reported enrollment target (92% lower).
The record links to 2 conditions, with Caffeine appearing as the primary indexed condition, and to 5 interventions - of which High Caffeine is the first listed.
NCT01924481 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT01924481 about?
NCT01924481 is a clinical study titled "Effects of a Cocoa Shot on the Human Brain". The Hershey Company is interested in investigating the effects of various chocolate beverages on brain physiology and cognitive function. The main substances in the drinks that are known to influence the brain are caffeine (and related chemicals such as theobromine) and flavonoids. Flavonoids are ch...
What is the current status of trial NCT01924481?
This trial is currently completed. It is a NA study. The enrollment target is 6 participants. The study started on 2013-09. Estimated completion is 2013-10.
What conditions does trial NCT01924481 study?
This clinical trial studies the following conditions: Caffeine, Flavonoids.
What interventions are being tested in trial NCT01924481?
The interventions under investigation include: High Caffeine (DIETARY_SUPPLEMENT), Low caffeine (DIETARY_SUPPLEMENT), High theobromine (DIETARY_SUPPLEMENT), low theobromine (DIETARY_SUPPLEMENT), No theobromine (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01924481?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01924481 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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