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NCT01919177 · ClinicalTrials.gov registry record · Phase 2

Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity

A Phase 2 study of Heart Failure With Normal Ejection Fraction, sponsored by Corporal Michael J. Crescenz VA Medical Center.

Completed
Registry status
Phase 2
Development phase
17
Enrollment target
1
Study location

NCT01919177 is a Phase 2 study of Heart Failure With Normal Ejection Fraction that has completed, run by Corporal Michael J. Crescenz VA Medical Center. The registered enrollment target is 17 participants, below the 638-participant average among 10 other Heart Failure With Normal Ejection Fraction trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT01919177, a Phase 2 study of Heart Failure With Normal Ejection Fraction, has completed, sponsored by Corporal Michael J. Crescenz VA Medical Center.

COMPLETED
Registry status
Phase 2
Development phase
17 participants
Enrollment target
1
Study location

Study Summary

The main objective is to test the hypothesis that inorganic nitrate supplementation will: (1) Improve exercise efficiency and performance; (2) Enhance the systemic vasodilator reserve during exercise and specifically, the vasodilator response in exercising muscle; (3) Reduce arterial wave reflections and arterial load; (4) Improve skeletal muscle mitochondrial function in subjects with heart failure with preserved ejection fraction.

Interventions

  • DIETARY_SUPPLEMENT Nitrate rich beetroot juice
  • DIETARY_SUPPLEMENT Nitrate depleted beetroot juice

Study Locations (1)

Pennsylvania

  • Philadelphia Veterans Affairs Medical Center - Philadelphia

Trial Details

FieldValue
Enrollment Target 17 participants
Start Date 2013-01
Est. Completion 2014-11
Phase Phase 2

What the Registry Record Tells You About NCT01919177

The ClinicalTrials.gov registry entry for NCT01919177 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 638-participant average among 10 other Heart Failure With Normal Ejection Fraction trials with a reported enrollment target (97% lower). The listed sponsor is Corporal Michael J. Crescenz VA Medical Center, which has 13 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Heart Failure With Normal Ejection Fraction appearing as the primary indexed condition, and to 2 interventions - of which Nitrate rich beetroot juice is the first listed.

NCT01919177 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT01919177 about?

NCT01919177 is a clinical study titled "Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity". The main objective is to test the hypothesis that inorganic nitrate supplementation will: (1) Improve exercise efficiency and performance; (2) Enhance the systemic vasodilator reserve during exercise and specifically, the vasodilator response in exercising muscle; (3) Reduce arterial wave reflection...

What is the current status of trial NCT01919177?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 17 participants. The study started on 2013-01. Estimated completion is 2014-11.

What conditions does trial NCT01919177 study?

This clinical trial studies the following conditions: Heart Failure With Normal Ejection Fraction.

What interventions are being tested in trial NCT01919177?

The interventions under investigation include: Nitrate rich beetroot juice (DIETARY_SUPPLEMENT), Nitrate depleted beetroot juice (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT01919177?

This trial is sponsored by Corporal Michael J. Crescenz VA Medical Center, which has 13 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01919177 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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