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NCT01919177 · ClinicalTrials.gov registry record · Phase 2
Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity
A Phase 2 study of Heart Failure With Normal Ejection Fraction, sponsored by Corporal Michael J. Crescenz VA Medical Center.
- Completed
- Registry status
- Phase 2
- Development phase
- 17
- Enrollment target
- 1
- Study location
NCT01919177: Completed Phase 2 study of Heart Failure With Normal Ejection Fraction, sponsored by Corporal Michael J. Crescenz VA Medical Center.
NCT01919177 is a Phase 2 study of Heart Failure With Normal Ejection Fraction that has completed, run by Corporal Michael J. Crescenz VA Medical Center. The registered enrollment target is 17 participants, below the 638-participant average among 10 other Heart Failure With Normal Ejection Fraction trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01919177, a Phase 2 study of Heart Failure With Normal Ejection Fraction, has completed, sponsored by Corporal Michael J. Crescenz VA Medical Center.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 17 participants
- Enrollment target
- 1
- Study location
Study Summary
The main objective is to test the hypothesis that inorganic nitrate supplementation will: (1) Improve exercise efficiency and performance; (2) Enhance the systemic vasodilator reserve during exercise and specifically, the vasodilator response in exercising muscle; (3) Reduce arterial wave reflections and arterial load; (4) Improve skeletal muscle mitochondrial function in subjects with heart failure with preserved ejection fraction.
Primary Outcome
We will assess the relationship between total power output and total O2 consumption (VO2, assessed via expired gas analysis) during a maximal-effort supine bicycle exercise test.
Conditions Studied
Interventions
- DIETARY_SUPPLEMENT Nitrate rich beetroot juice
- DIETARY_SUPPLEMENT Nitrate depleted beetroot juice
Study Locations (1)
Pennsylvania
- Philadelphia Veterans Affairs Medical Center - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2013-01 |
| Est. Completion | 2014-11 |
| Phase | Phase 2 |
What the finished NCT01919177 record still lists
NCT01919177 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 17 participants, a relatively small participant target, below the 638-participant average among 10 other Heart Failure With Normal Ejection Fraction trials with a reported enrollment target (97% lower).
The record links to 1 condition, with Heart Failure With Normal Ejection Fraction appearing as the primary indexed condition, and to 2 interventions - of which Nitrate rich beetroot juice is the first listed.
NCT01919177 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01919177 about?
NCT01919177 is a clinical study titled "Effect of Inorganic Nitrates (Beetroot Juice) on Arterial Hemodynamics and Exercise Capacity". The main objective is to test the hypothesis that inorganic nitrate supplementation will: (1) Improve exercise efficiency and performance; (2) Enhance the systemic vasodilator reserve during exercise and specifically, the vasodilator response in exercising muscle; (3) Reduce arterial wave reflection...
What is the current status of trial NCT01919177?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 17 participants. The study started on 2013-01. Estimated completion is 2014-11.
What conditions does trial NCT01919177 study?
This clinical trial studies the following conditions: Heart Failure With Normal Ejection Fraction.
What interventions are being tested in trial NCT01919177?
The interventions under investigation include: Nitrate rich beetroot juice (DIETARY_SUPPLEMENT), Nitrate depleted beetroot juice (DIETARY_SUPPLEMENT).
Who is sponsoring clinical trial NCT01919177?
This trial is sponsored by Corporal Michael J. Crescenz VA Medical Center, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01919177 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01919177's enrollment target sits among peer trials
17 10th of 10 higher than 1 of 10 other Heart Failure With Normal Ejection Fraction trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Heart Failure With Normal Ejection Fraction trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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