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NCT01889719 · ClinicalTrials.gov registry record · Phase 1

A Phase I Study to Evaluate the Safety and Immunogenicity of Heterologous Boost Immunizations With MVA-CMDR

A Phase 1 study of HIV, sponsored by Rockefeller University.

Completed
Registry status
Phase 1
Development phase
14
Enrollment target
1
Study location

NCT01889719: Completed Phase 1 study of HIV, sponsored by Rockefeller University.

NCT01889719 is a Phase 1 study of HIV that has completed, run by Rockefeller University. The registered enrollment target is 14 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01889719, a Phase 1 study of HIV, has completed, sponsored by Rockefeller University.

COMPLETED
Registry status
Phase 1
Development phase
14 participants
Enrollment target
1
Study location

Study Summary

This trial will investigate whether immunizations with an MVA recombinant HIV vaccine are safe and whether they will boost immune responses generated by immunizations with a dendritic cell (DC) targeted protein vaccine, DCVax-001, plus poly ICLC in healthy HIV-uninfected volunteers.

Primary Outcome

safety and tolerability of two intramuscular injections of MVA-CMDR vaccine candidate in healthy HIV-uninfected volunteers

Conditions Studied

Interventions

  • BIOLOGICAL MVA-CMDR

Study Locations (1)

New York

  • The Rockefeller University - New York

Trial Details

FieldValue
Enrollment Target 14 participants
Start Date 2014-01
Est. Completion 2015-05
Phase Phase 1
Rockefeller University

117 total trials

What the finished NCT01889719 record still lists

NCT01889719 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 14 participants, a relatively small participant target, below the 440-participant average among 303 other HIV trials with a reported enrollment target (97% lower).

The record links to 1 condition, with HIV appearing as the primary indexed condition, and to 1 intervention - of which MVA-CMDR is the first listed.

NCT01889719 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT01889719 about?

NCT01889719 is a clinical study titled "A Phase I Study to Evaluate the Safety and Immunogenicity of Heterologous Boost Immunizations With MVA-CMDR". This trial will investigate whether immunizations with an MVA recombinant HIV vaccine are safe and whether they will boost immune responses generated by immunizations with a dendritic cell (DC) targeted protein vaccine, DCVax-001, plus poly ICLC in healthy HIV-uninfected volunteers.

What is the current status of trial NCT01889719?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 14 participants. The study started on 2014-01. Estimated completion is 2015-05.

What conditions does trial NCT01889719 study?

This clinical trial studies the following conditions: HIV.

What interventions are being tested in trial NCT01889719?

The interventions under investigation include: MVA-CMDR (BIOLOGICAL).

Who is sponsoring clinical trial NCT01889719?

This trial is sponsored by Rockefeller University, which has 117 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01889719 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01889719's enrollment target sits among peer trials

14 290th of 303 higher than 12 of 303 other HIV trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other HIV trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01889719, the US trial registry maintained by the National Library of Medicine. NCT01889719 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.