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NCT01841723 · ClinicalTrials.gov registry record · Phase 2
Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia
A Phase 2 study of Hairy Cell Leukemia and Recurrent Hairy Cell Leukemia, sponsored by National Cancer Institute (NCI).
- Active
- Registry status
- Phase 2
- Development phase
- 44
- Enrollment target
- 5
- Study locations
NCT01841723: Active Phase 2 study of Hairy Cell Leukemia and Recurrent Hairy Cell Leukemia, sponsored by National Cancer Institute (NCI).
NCT01841723 is a Phase 2 study of Hairy Cell Leukemia and Recurrent Hairy Cell Leukemia that is active but no longer recruiting, run by National Cancer Institute (NCI). The registered enrollment target is 44 participants, below the 70-participant average among 15 other Hairy Cell Leukemia trials with a reported enrollment target (37% lower). The trial reports 5 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01841723, a Phase 2 study of Hairy Cell Leukemia and Recurrent Hairy Cell Leukemia, is active but no longer recruiting, sponsored by National Cancer Institute (NCI).
- ACTIVE NOT RECRUITING
- Registry status
- Phase 2
- Development phase
- 44 participants
- Enrollment target
- 5
- Study locations
Study Summary
This phase II trial studies how well ibrutinib works in treating patients with hairy cell leukemia that has returned after a period of improvement. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
Primary Outcome
Calculated as the proportion of patients who achieve a PR or CR to therapy within the first 32 weeks of therapy divided by the total number of evaluable patients.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- PROCEDURE Bone Marrow Aspiration
- PROCEDURE Bone Marrow Biopsy
- PROCEDURE Computed Tomography
- DRUG Ibrutinib
Study Locations (5)
Maryland
- National Institutes of Health Clinical Center - Bethesda
Michigan
- Wayne State University/Karmanos Cancer Institute - Detroit
Minnesota
- Mayo Clinic in Rochester - Rochester
Ohio
- Ohio State University Comprehensive Cancer Center - Columbus
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2013-04-30 |
| Est. Completion | 2029-12-31 |
| Phase | Phase 2 |
What the registry record for NCT01841723 still lists
NCT01841723 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 70-participant average among 15 other Hairy Cell Leukemia trials with a reported enrollment target (37% lower).
The record links to 4 conditions, with Hairy Cell Leukemia appearing as the primary indexed condition, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT01841723 lists 5 locations in 5 states (Maryland, Michigan, Minnesota).
Frequently Asked Questions
What is clinical trial NCT01841723 about?
NCT01841723 is a clinical study titled "Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia". This phase II trial studies how well ibrutinib works in treating patients with hairy cell leukemia that has returned after a period of improvement. Ibrutinib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
What is the current status of trial NCT01841723?
This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 44 participants. The study started on 2013-04-30. Estimated completion is 2029-12-31.
What conditions does trial NCT01841723 study?
This clinical trial studies the following conditions: Hairy Cell Leukemia, Recurrent Hairy Cell Leukemia, Recurrent Hairy Cell Leukemia Variant, Hairy Cell Leukemia Variant.
What interventions are being tested in trial NCT01841723?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Bone Marrow Aspiration (PROCEDURE), Bone Marrow Biopsy (PROCEDURE), Computed Tomography (PROCEDURE), Ibrutinib (DRUG).
Who is sponsoring clinical trial NCT01841723?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01841723 being conducted?
This trial has 5 study locations across Maryland, Michigan, Minnesota, Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hairy Cell Leukemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01841723's enrollment target sits among peer trials
44 10th of 15 higher than 6 of 15 other Hairy Cell Leukemia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Hairy Cell Leukemia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL)
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