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NCT01781637 · ClinicalTrials.gov registry record · Phase 1
Peanut Reactivity Reduced by Oral Tolerance in an Anti-IgE Clinical Trial
A Phase 1 study of Food Allergy and Peanut Allergy, sponsored by Boston Children's Hospital.
- Completed
- Registry status
- Phase 1
- Development phase
- 36
- Enrollment target
- 4
- Study locations
NCT01781637: Completed Phase 1 study of Food Allergy and Peanut Allergy, sponsored by Boston Children's Hospital.
NCT01781637 is a Phase 1 study of Food Allergy and Peanut Allergy that has completed, run by Boston Children's Hospital. The registered enrollment target is 36 participants, below the 962-participant average among 17 other Food Allergy trials with a reported enrollment target (96% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01781637, a Phase 1 study of Food Allergy and Peanut Allergy, has completed, sponsored by Boston Children's Hospital.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 36 participants
- Enrollment target
- 4
- Study locations
Study Summary
The investigators will perform a double blind, placebo controlled clinical trial with Xolair (omalizumab) at four centers to safely and rapidly desensitize patients with severe peanut allergy. The investigators will determine if pretreatment with anti-IgE mAb (Xolair/omalizumab) can greatly reduce allergic reactions and allow for faster and safer desensitization.
Conditions Studied
Interventions
- DRUG placebo
- DRUG Omalizumab
Study Locations (4)
California
- Stanford University - Stanford
Illinois
- Lurie Children's Hospital - Chicago
Massachusetts
- Division of Immunology, Children's Hospital Boston - Boston
Pennsylvania
- Children's Hospital of Philadelphia - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 36 participants |
| Start Date | 2013-01 |
| Est. Completion | 2022-05-31 |
| Phase | Phase 1 |
What the finished NCT01781637 record still lists
NCT01781637 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 36 participants, a relatively small participant target, below the 962-participant average among 17 other Food Allergy trials with a reported enrollment target (96% lower).
The record links to 2 conditions, with Food Allergy appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.
NCT01781637 reports a single indexed study location in California, Illinois, Massachusetts.
Frequently Asked Questions
What is clinical trial NCT01781637 about?
NCT01781637 is a clinical study titled "Peanut Reactivity Reduced by Oral Tolerance in an Anti-IgE Clinical Trial". The investigators will perform a double blind, placebo controlled clinical trial with Xolair (omalizumab) at four centers to safely and rapidly desensitize patients with severe peanut allergy. The investigators will determine if pretreatment with anti-IgE mAb (Xolair/omalizumab) can greatly reduce a...
What is the current status of trial NCT01781637?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 36 participants. The study started on 2013-01. Estimated completion is 2022-05-31.
What conditions does trial NCT01781637 study?
This clinical trial studies the following conditions: Food Allergy, Peanut Allergy.
What interventions are being tested in trial NCT01781637?
The interventions under investigation include: placebo (DRUG), Omalizumab (DRUG).
Who is sponsoring clinical trial NCT01781637?
This trial is sponsored by Boston Children's Hospital, which has 462 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01781637 being conducted?
This trial has 4 study locations across California, Illinois, Massachusetts, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT01781637's enrollment target sits among peer trials
36 13th of 17 higher than 5 of 17 other Food Allergy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Food Allergy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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