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NCT02226276 · ClinicalTrials.gov registry record · NA

Copper Cu 64-DOTA-Trastuzumab PET in Predicting Response to Treatment With Ado-Trastuzumab Emtansine in Patients With Metastatic HER2 Positive Breast Cancer

A NA study of HER2-positive Breast Cancer and Stage IV Breast Cancer, sponsored by City of Hope Medical Center.

Active
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT02226276 is a NA study of HER2-positive Breast Cancer and Stage IV Breast Cancer that is active but no longer recruiting, run by City of Hope Medical Center. The registered enrollment target is 10 participants, below the 239-participant average among 54 other HER2-positive Breast Cancer trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02226276, a NA study of HER2-positive Breast Cancer and Stage IV Breast Cancer, is active but no longer recruiting, sponsored by City of Hope Medical Center.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

This pilot clinical trial studies how well copper Cu 64-tetra-azacyclododecanetetra-acetic acid (DOTA)-trastuzumab positron emission tomography (PET) works in predicting response to treatment with ado-trastuzumab emtansine in patients with human epidermal growth factor receptor 2 (HER2) positive breast cancer that has spread to other places in the body. Copper Cu 64-DOTA-trastuzumab is a chemotherapy drug (trastuzumab) attached to a radioactive substance. Diagnostic procedures using PET may allow scanners to take pictures of where the drug travels in the body and may help doctors identify which patients may benefit from treatment with ado-trastuzumab emtansine.

Interventions

  • RADIATION fludeoxyglucose F 18
  • PROCEDURE positron emission tomography
  • PROCEDURE computed tomography
  • BIOLOGICAL trastuzumab
  • RADIATION copper Cu 64-DOTA-trastuzumab

Study Locations (1)

California

  • City of Hope Medical Center - Duarte

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2015-01-07
Est. Completion 2026-09-29
Phase NA

Sponsor

City of Hope Medical Center

582 total trials

What the Registry Record Tells You About NCT02226276

The ClinicalTrials.gov registry entry for NCT02226276 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 239-participant average among 54 other HER2-positive Breast Cancer trials with a reported enrollment target (96% lower). The listed sponsor is City of Hope Medical Center, which has 582 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with HER2-positive Breast Cancer appearing as the primary indexed condition, and to 5 interventions - of which fludeoxyglucose F 18 is the first listed.

NCT02226276 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT02226276 about?

NCT02226276 is a clinical study titled "Copper Cu 64-DOTA-Trastuzumab PET in Predicting Response to Treatment With Ado-Trastuzumab Emtansine in Patients With Metastatic HER2 Positive Breast Cancer". This pilot clinical trial studies how well copper Cu 64-tetra-azacyclododecanetetra-acetic acid (DOTA)-trastuzumab positron emission tomography (PET) works in predicting response to treatment with ado-trastuzumab emtansine in patients with human epidermal growth factor receptor 2 (HER2) positive bre...

What is the current status of trial NCT02226276?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2015-01-07. Estimated completion is 2026-09-29.

What conditions does trial NCT02226276 study?

This clinical trial studies the following conditions: HER2-positive Breast Cancer, Stage IV Breast Cancer, Liver Metastases, Recurrent Breast Cancer, Bone Metastases.

What interventions are being tested in trial NCT02226276?

The interventions under investigation include: fludeoxyglucose F 18 (RADIATION), positron emission tomography (PROCEDURE), computed tomography (PROCEDURE), trastuzumab (BIOLOGICAL), copper Cu 64-DOTA-trastuzumab (RADIATION).

Who is sponsoring clinical trial NCT02226276?

This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02226276 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.